Two-year senior technician post in brown algal functional genomics (M/F)
New
- IT in FTC
- 24 mounth
- Doctorate
Offer at a glance
The Unit
Laboratoire de Biologie Intégrative des Modèles Marins
Contract Type
IT in FTC
Working hHours
Full Time
Workplace
29688
Contract Duration
24 mounth
Date of Hire
20/04/2026
Remuneration
Between 3143 € and 3645 € per month before tax, depending on the level of experience of the candidate
Apply Application Deadline : 19 March 2026 23:59
Job Description
Missions
Senior technician in brown algal molecular genetics
Histones are important regulatory components of eukaryotic chromatin and variant forms of histone proteins have been shown to play crucial roles in diverse biological processes in both animals and land plants. Following up on the recent identification of three novel algal variants of the histone H2A protein, the ANR project His2AVar aims to investigate the functional roles of these novel variants in Stramenopiles, with a particular focus on brown algae in the laboratory that is hosting this senior technician post.
The candidate will use CRISPR methodology developed in the host laboratory to delete histone H2A loci in the brown algal model organism Ectocarpus. The phenotypes of the resulting mutants will then be analysed at both the morphological and molecular levels, the latter involving both transcriptomic analysis and chromatin analysis using ChIP-seq.
Activity
The project will involve maintenance and growth of wild type and mutant Ectocarpus strains, application of CRISPR methodology to generate new mutant lines and phenotypic characterisation of newly created mutant lines. Phenotyping will employ a range of different approaches including morphometry, cell biology approaches, transcriptomic and epigenetic approaches. Protocols are available in the host laboratory for all these approaches.
Your Profil
Skills
The candidate should have experience with standard molecular biology and cell biology (microscopy) approaches and experience working with CRISPR methodology and/or handling brown algae in culture. Standard bioinformatic skills, for example the capacity to handle transcriptomic data, would also be appreciated.
Your Work Environment
The host institute, the Station Biologique de Roscoff (SBR, http://www.sb-roscoff.fr/about-roscoff-marine-station/missions.html), is a centre of marine biology and oceanographic research situated in the town of Roscoff on the north coast of Brittany (France) about 60 km east of Brest. The SBR has about 200 permanent employees.
The postdoctoral fellowship is financed by the "Agence Nationale de la Recherche" (ANR) project His2AVar. The project will involve strong collaborative interactions with the Unit of Biologic Sciences and Biotechnologies (UMR6286) in Nantes and the Institute of Genetics, Reproduction and Development (UMR6293) in Clermont-Ferrand.
Compensation and benefits
Compensation
Between 3143 € and 3645 € per month before tax, depending on the level of experience of the candidate
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8227-JERCOC-019 |
|---|---|
| Line of business | Life, Earth and Environmental Sciences |
| Job Type | Biological Data Analysis Engineer |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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