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Portal > Offres > Offre UMR8226-PHIMEY-001 - Post-doc Biologie Structurale Chaperons Moléculaires Paris (H/F)

Post-doc in chaperone structural biology, Paris (M/W)

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR8226-PHIMEY-001
Workplace : PARIS 05
Date of publication : Tuesday, December 03, 2019
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 January 2020
Proportion of work : Full time
Remuneration : 2600 et 3107 € gross monthly according to experience
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

We are looking for a highly motivated post-doctoral research scientist to work on chaperone-mediated protein translocation. Our team is studying the mechanisms of action of molecular chaperones during protein folding, assembly and translocation. We are particularly interested in the structure / function analysis of the molecular chaperones Hsp70 and Hsp90 and in the mechanisms of their regulation by their cochaperones.

Activities

The project will combine a wide range of approaches from molecular biology, protein biochemistry to biophysics and crystallography.

The successful candidate will:
- contribute to the design of the project,
- develop the methodologies,
- perform the experiments,
- analyze and communicate his data,
- write scientific articles.

Skills

The candidate must have a PhD in Biochemistry or Structural Biology with a demonstrated track record of productive research. He / she will have a good command of molecular biology tools, an expertise in protein production and purification, and solid experience in crystallography. An experience in cryo-EM would be an asset.
The candidate must possess excellent organizational and team working abilities, as well as verbal and written communication skills in English (French is not mandatory).

Work Context

The work will be carried out within the "Molecular chaperones and biogenesis of macromolecular assemblies" team at the Laboratory of Molecular and Cellular Biology of Eukaryote (UMR8226, CNRS - Sorbonne University; http://www.lbmce.ibpc.fr) in the Institut de Biologie Physico-Chimique (IBPC) in Paris.
The IBPC, created in 1930 by the Edmond de Rothschild Foundation, has a multidisciplinary vocation to promote research in all fields of biology and offers an exceptional scientific environment of opening on all disciplines. It enjoys a location in the heart of Paris, in the student district (Latin Quarter) and the Montagne Sainte-Geneviève hosting the highest concentration of research institution in the city.

Constraints and risks

Travels outside the institute will be required for access to synchrotrons.

Additional Information

The position is funded for a fixed term for 1 year with the possibil
of extension for 1 more year. The position can start in January 1st 2020. Applications including a CV and a cover letter, as well as the contact details of 2 to 3 referees, should be submitted through this website.

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