Postdoctoral Researcher (M/F) in Time-Encoded Single-Molecule Fluorescence Microscopy for Ultrafast Imaging
- Researcher in FTC
- 24 mounth
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut des Sciences Moléculaires d'Orsay
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
91405 ORSAY
Contract Duration
24 mounth
Date of Hire
01/05/2026
Remuneration
Gross monthly salary depending on experience: For a researcher with less than 2 years experience after the PhD: 3131,32 € - between 2 and 7 years experience: 4341,70 €
Apply Application Deadline : 01 May 2026 00:00
Job Description
Missions
Within the framework of the ERC TimeNanoLive project, the mission will be to develop a new generation of fluorescence microscopy methods aimed at overcoming current limitations in acquisition time for single-molecule imaging. The project explores original strategies for temporal encoding of information, inspired by concepts from single-pixel imaging, and transposed to fluorescence microscopy through the use of structured illumination with variable frequency.
The objective is to shift a critical part of the spatial and photophysical information into the temporal domain, in order to drastically reduce the number of photons and the acquisition time required for image reconstruction, while preserving ultimate precision in single-molecule localization and access to key photophysical parameters (fluorescence lifetime, brightness, molecular dynamics).
This approach paves the way toward ultrafast imaging, compatible with the observation of living biological systems, while remaining applicable to the study of nanostructures and functional materials. The recruited researcher will contribute to experimental design, modelling of temporal encoding schemes, and data analysis, within a highly interdisciplinary environment combining optics, photophysics, signal processing and biology.
Activity
The person will contribute to various aspects:
- setting up the optical implementations of new concepts
- testing and validation of new experimental set-ups
- pilot/simulation programming
- characterisation of various samples
- supervising student (intership, PhD candidate)
- writing articles
- taking part in conferences
Your Profil
Skills
- physics with knowledge in optics
- knowledge in microscopy
- knowledge in single-molecule imaging (acquisition and processing)
- knowledge in photophysics
- knowledge in cell culture
- python programming
Your Work Environment
This work will be carried out within ISMO (Unité Mixte CNRS / Université Paris-Saclay) as part of a European proejct ERC TimeNanolive. The laboratory has an on-site culture room and various microscopes for single molecule localization microscopy.
Compensation and benefits
Compensation
Gross monthly salary depending on experience: For a researcher with less than 2 years experience after the PhD: 3131,32 € - between 2 and 7 years experience: 4341,70 €
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8214-SANLEV-038 |
|---|---|
| CN Section(s) / Research Area | Interactions, particles, nuclei, from laboratory to cosmos |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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