Postdoctoral contract in chemometrics and chemoinformatics of metabolic diseases by UHPLC-HRMS (M/F)
New
- Researcher in FTC
- 6 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Multi-omique et physiopathologie des maladies métaboliques
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
59045 LILLE
Contract Duration
6 months
Date of Hire
01/01/2027
Remuneration
Between €3,021.50 and €4,208.27 gross per month, depending on experience
Apply Application Deadline : 29 October 2026 23:59
Job Description
Missions
A Postdoctoral position is available at the METAB-OMICS Unit, UMR 8199/ U1283 CNRS, INSERM, Institut Pasteur de Lille, CHU Lille, Université Lille) in the “Metabolome, Microbiome and Metabolic Diseases” team and the metabolomic platform IMPACT-PM, directed by Prof. Marc-Emmanuel Dumas in Lille, France.
The successful candidate will be responsible for developing and implementing innovative chemoinformatic and chemometric workflows for high-throughput high-resolution accurate mass-based metabolomic data and advanced AI analytics to efficiently mine and analyse LC-MS-based metabolomic data and to provide biological insight on the role of microbial metabolites in metabolic diseases.
He/She will contribute to the development of an AI-based strategies for MS annotation based on a database of pure standards through automated peak-picking and spectral matching functionalities, and downstream statistical and pathway analysis.
Activity
The successful candidate will handle and processing of LC-MS data generated by the Team:
• chemical data flows
• data pre-processing methodologies for untargeted metabolic profiles
• development of AI-based chemoinformatic workflows for structural assignment
• chemoinformatic analyses (chemical taxonomy, MACCS fingerprints, chemical similarity)
• integrative multi-omic analyses through chemometrics, Machine Learning and AI
He/She will be responsible for data processing and scientific dissemination of results (drafting of scientific articles in English and participation in conferences). The successful candidate will play a role in influencing the project: design of workflow, optimisation and benchmarking, prioritisation of projects, interpretation of results.
Your Profil
Skills
The candidate will:
• hold a PhD in computer science, bioinformatics, chemoinformatics or similar subject
• have experience in AI and ML
• have experience in analysing mass spectrometry data
• master the English language (written and spoken)
• have an interest in multidisciplinary work
• demonstrate autonomy, rigor, critical thinking, problem solving and ability to work within an international team
Your Work Environment
The successful candidate will join the “Metabolome, Microbiome and Metabolic Diseases” team at UMR8199/1283 METAB-OMICS (head: Amélie Bonnefond), whose research objectives are to study the microbiome and its metabolic output to identify novel microbial compounds and characterise their bioactivities in metabolic diseases. The Unit provides an excellent intellectual environment and most of the infrastructure required to carry out the project, with direct access to state-of-the-art platforms including metabolomics by high-resolution mass spectrometry (IMPACT-PM), high-throughput sequencing (LIGAN-PM, 'Equipment of Excellence' platform award). More specifically, the candidate will join Prof. Dumas' team. The researcher will strongly interact with colleagues within the group, the Institute and international collaborators at Imperial College London, through the CNRS- Imperial “Antoine Lavoisier” International Research Lab on Multiscale Metabolism.
Compensation and benefits
Compensation
Between €3,021.50 and €4,208.27 gross per month, depending on experience
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8199-HELDEG0-049 |
|---|---|
| CN Section(s) / Research Area | Physiology, ageing, tumorigenesis |
| Relevant experience | 1 to 4 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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