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General information
Reference : UMR8197-NATBOI-055
Workplace : PARIS 05
Date of publication : Monday, December 21, 2020
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 March 2021
Proportion of work : Full time
Remuneration : Gross salary between 3100 and 3840 depending on expérience
Desired level of education : PhD
Experience required : Indifferent
Missions
The goal of the proposed project is to develop methods for the integration of multi-omics single-cell datasets. The applicant will in particular work on the development of a network-based approach for reconstructing the multi-omics regulatory mechanisms underlying cell types.
Activities
The person recruited will be the main contributor for the development of single-cell network-based multi-omics integrative methods. The work will include the implementation of open-source software.
The successful applicant will work in an interdisciplinary team of computational biologists, bioinformaticians and systems biologists. The project will be developed in close collaboration with Sanofi in the context of the Sanofi iTechAwards program, as well as with Anaïs Baudot (Marseille), biological network expert.
Skills
PhD in Computational Biology, Bioinformatics, Computer Science, Applied Mathematics, Systems Biology or related fields.
Experience in the design and implementation of algorithms applied to the analysis of a variety
of biological data, as well as strong programming (R, Python...) and communication skills are required.
Previous knowledge in network theory, network inference in single-cell or bulk data and multiplex networks would further be appreciated.
Work Context
The Institute of Biology of the Ecole Normale Supérieure (IBENS) is a multidisciplinary research center in Biology. IBENS is a mixed ENS-CNRS-INSERM unit with over 300 staff members working 30 research teams, conveniently located in the Latin Quarter in downtown Paris.
IBENS researchers cover a wide range of disciplines, including evolutionary biology, ecology, computational biology, genetics, and comparative genomics.
The host team, Computational Systems Biology (CSB), directed by Denis Thieffry includes three permanent researchers and two PhDs.
The aim of the group is to develop efficient algorithms for the analysis of omics data and for the computational modelling of biological networks.
The candidate will work in close collaboration with Anaïs Baudot (MMG Marseille) and he/she will contribute to a collaborative project with Sanofi.
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