M/F Engineer in molecular engineering for the delivery of therapeutic mRNA by extracellular vesicles
New
- IT in FTC
- 12 months
- BAC+5
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
NAnomédecine, Biologie extracellulaire, Intégratome et Innovations
Contract Type
IT in FTC
Working hHours
Full Time
Workplace
75006 PARIS 06
Contract Duration
12 months
Date of Hire
01/10/2026
Remuneration
from 2571 € gross per month
Apply Application Deadline : 30 July 2026 23:59
Job Description
Missions
The candidate will genetically modify mesenchymal stromal cells to enrich the extracellular vesicles they release with specific messenger RNAs. He/she will characterize the mechanisms governing mRNA targeting to the vesicles and analyze the extracellular vesicles using various methods. He/she will also investigate the capacity of these modified extracellular vesicles to deliver mRNA to recipient cells.
Activity
Molecular modification of mesenchymal stromal cells; Molecular engineering of cells and characterization; Bioproduction of extracellular vesicles; Multimodal characterization of extracellular vesicles
Your Profil
Skills
Interdisciplinary skills, particularly in cell engineering, cell biology, multimodal characterization and molecular modeling.
Your Work Environment
The new multidisciplinary unit NABI (Nanomedicine, Extracellular Biology, Integratome and Health Innovations), located on the Saint Germain Campus of Université Paris Cité (45 rue des Saints Pères, 75006 Paris), was established on January 1, 2025. It brings together around 70 collaborators—including physicists, biologists, pharmacists, engineers, and physicians—of which about thirty are permanent staff, under the joint supervision of CNRS, INSERM, and Université Paris Cité.
NABI's scientific objectives are to develop new therapies based on biological nano-objects (extracellular vesicles) or synthetic nano-objects (activatable metallic nanoparticles) for the delivery of personalized treatments for hard-to-treat diseases.
Studying nano-objects in biological fluids requires transdisciplinary approaches (physics, engineering, cell and molecular biology, immunology, etc.) extending all the way to clinical practice, as well as dedicated technical and analytical resources (super-resolution microscopy, nanosensors, microfluidics, etc.), combined with systematic multimodal and multiscale exploration supported by AI-driven analysis.
These innovative methodologies are developed within NABI and in partnership with the industrial integrator IVETh, a technology hub dedicated to the characterization, bioproduction, and engineering of extracellular vesicles and nanovectors for diagnostics and personalized therapies.
The engineer will integrate the Nanobiotherapy team, in the framework of the European network for rare diseases ERDERA.
Compensation and benefits
Compensation
from 2571 € gross per month
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR8175-FLOGAZ0-016 |
|---|---|
| Line of business | Life, Earth and Environmental Sciences |
| Job Type | Biological Techniques Engineer |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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