General information
Offer title : Postdoc Fellow (epi)genomics and culturing of protists (M/F) (H/F)
Reference : UMR8079-LAUEME0-001
Number of position : 1
Workplace : GIF SUR YVETTE
Date of publication : 07 May 2024
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 August 2024
Proportion of work : Full time
Remuneration : Monthly gross salary: between 3081,33 and 3519,85 euros depending on experience
Desired level of education : Niveau 8 - (Doctorat)
Experience required : 1 to 4 years
Section(s) CN : Organisation, expression and evolution of genomes Bioinformatics and systems biology
Missions
The candidate will work on a project that aims, among other things, to better understand the diversity and evolution of epigenetic modifications in eukaryotic microbes (protists).
During his/her PhD, the candidate will take part in 1) preparing genetic material (RNA and DNA) for transcriptome, genome and methylome sequencing, and 2) their subsquent assembly, annotation and various other bioinformatic investigations.
Activities
More specifically, they will be in charge of the following tasks:
- preparation and maintenance of protist cultures, with an emphasis on under-studied lineages;
- RNA/DNA extraction for various NGS sequencing techniques (Illumina, Nanopore, Hi-C, bisulfite…), from cultures or, in the case of organismes difficult to grow at high density, directly from single-cells;
- sequence assembly and annotation in order to obtain high-quality genome data;
- bioinformatic investigation of the epigenome;
- phylogenetic reconstruction of specific genes of interest.
Skills
We will prioritize candidates with an excellent background in bioinformatics (transcriptome and/or genome analyses including assembly, data cleaning, annotation, and molecular phylogenetics). Alternatively, we will consider candidates with microbiology background (culture maintenance, genetic material preparation for sequencing), under the condition that they show a real enthusiasm to acquire an expertise in bioinformatics. This is an ambitious project which will require commitment and thoroughness.
- You must have validated a PhD
- English proviciency (written and spoken).
- Good presentation and communication skills
- Autonomy and organization
- Synthetic mind and critical thinking
Work Context
The Ecology, Systematics and Evolution (ESE) unit is coaffiliated CNRS – Paris-Saclay - AgroParisTech, and is located on the Paris-Saclay campus, in Gif-sur-Yvette (20 kms South of Paris).
The candidate will be a member of the DEEM team (Diversity, Ecology et Evolution of Microbes: http://www.deemteam.fr/en), which focuses on microorganismal diversity and evolution, using molecular phylogenetics and comparative genomics.
Our team is international and the working langage is English.