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Portal > Offres > Offre UMR8000-PHIMAI0-006 - Postdoctorat (H/F): Analyse de mélanges biologiques complexes par spectrométrie de masse, mobilité ionique et infrarouge

Postdoc fellowship (M/F) : Analysis of complex mixtures by mass spectrometry, ion mobility, and infr

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR8000-PHIMAI0-006
Workplace : ORSAY
Date of publication : Thursday, August 01, 2019
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 November 2019
Proportion of work : Full time
Remuneration : Monthly gross salary would be between 2500 and 3000 depending on past experience
Desired level of education : PhD
Experience required : Indifferent

Missions

Development of a new instrument and analytical method based on mass spectrometry and application to the identification and quantification of biomarkers of metabolic diseases.

Activities

Development and adaptation a new analytical method based on the coupling of mass spectrometry, ion mobility separation, and identification through infrared activation;
Participation to the development and adaptation of new ion mobility devices, with the support of a technical team;
Adaptation of procedure and experimental conditions for sample preparation;
Analysis, exploitation, and interpretation of data;
Dissemination of the results;
Participation to the user' training;
Diagnosis of dysfunction of the experimental setup.

Skills

First degree in chemistry or biochemistry and PhD or equivalent in analytical chemistry;
Work experience required in mass spectrometry;
Work experience with separation technique such as chromatography or ion mobility will be valued;
Work experience with Mathematical and numerical tools associated with data treatment;
Training and practice with sample preparation techniques;
Skills with literature search tools;
Good knowledge in computer control of setup and data acquisition;
Strong analytical capacity;
English (level B2-).

Work Context

This research project will take place in the Laboratoire de Chimie Physique (LCP), under the responsability of Philippe Maître, CNRS senior research director. The research team currently consists in 2 PhD students, 1 assistant professor, an invited professor, and a research director. This team is part of the RISMAS group, one of the four research group at LCP. Two platforms will be used: SMAS and CLIO.

Technical support will be provided in mass spectrometry (1 IE CNRS), mechanical design and fabrication (1 AI CNRS) and electronics (1 AI CNRS).

This research project is cofounded by the Agence National de la Recherche (ANR) for two years.

Le projet de recherche est cofinancé par l'Agence Nationale de la Recherche (ANR) pour deux ans. It is part of a collaboration with the team of Jean-François Benoist, professor at Université Paris-Sud, working at PROTECT (Univ. Paris Diderot), and head of a biochemistry laboratory in a university hospital at Robert Debré hospital (Paris).

Bimonthly one-day meetings of the two PIs will be organized to discuss and monitor the progress based on reports of the different persons involved.

LCP is a joint research laboratory (UMR 8000) of the Université Paris-Sud and CNRS, located on the campus of the faculty of science at Orsay (builidings 349, 350, and 201), and it includes nearly 130 persons, including 80 staff members. LCP aims at (i) performing fundamental research in physical chemistry in condensed phase, gas phase, as well as in life sciences, (ii) developping innovative methodologies, either experimental or numerical, (iii) contributing to the economical valorisation of these developments, (iv) ensuring the effective operation of plateforms CLIO, ELYSE, SMAS, and gamma source, (v) contributing to the teaching of physical chemistry at Université Paris-Sud.

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