Reference : UMR7622-MICLAB1-002
Workplace : PARIS 05
Date of publication : Thursday, September 22, 2022
Type of Contract : FTC Technical / Administrative
Contract Period : 24 months
Expected date of employment : 1 December 2022
Proportion of work : Full time
Remuneration : 2173-2294 €/ gross per month depending on level of experience
Desired level of education : 5-year university degree
Experience required : Indifferent
The aim of the project is to study the contribution of mechanical forces to the immune response. In particular, it will assess whether the mechanical changes observed during small injuries or infection influence the dynamics of the cytoskeleton characteristic of the immune response. The model used will be the nematode C. elegans, an organism that lends itself very well to cellular studies.
- Generation of strains carrying mutations and fluorescent markers by genetic crossing
- Observations of markers by confocal microscopy
- Introduction of micro-injuries by laser
- Quantification of images
- Presentation of the results in lab-meetings
- Master in cell biology or genetics
- Experience in imaging would be a plus
- English level of at least B2 essential
The work will be carried out in Michel Labouesse's team at the Institut de Biologie Paris-Seine (IBPS), Developmental Biology Unit. The Institut de Biologie Paris-Seine (https://www.ibps.sorbonne-universite.fr/fr), where about 500 people work, is located on the Jussieu campus of Sorbonne University. The IBPS teams have interests ranging from computational biology to physics, developmental biology and neuroscience. The work will be supervised by Michel Labouesse and by a senior lecturer from the team participating in the project.
This project is part of a contract financed by an ANR project, which will be carried out in collaboration with Nathalie Pujol's team at the CIML (Marseille), as well as Raphaël Voituriez (IBPS) for the theoretical aspects. Visits to our collaborator, Nathalie Pujol, in Marseille are possible.
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