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Reference : UMR7592-ISALAD-016
Workplace : PARIS 13
Date of publication : Friday, November 08, 2019
Type of Contract : FTC Scientist
Contract Period : 30 months
Expected date of employment : 1 January 2020
Proportion of work : Full time
Remuneration : between 2 695,56 and 3 600 € gross salary depending on experience.
Desired level of education : PhD
Experience required : Indifferent
DNA methylation is a stable epigenetic mark, however in early mammalian development, global DNA methylation levels are dramatically remodeled. The candidate will use a computational approach in order to discover non-conventional forms of DNA methylation-based regulation in this window of development, and eventually test the epigenetic impact in cellula and in vivo.
Bioinformatics: Computational analysis of NGS-generated data sets
Cell culture : Mouse embryonic stem cell culture and differentiation, CRISPR-mediated genome and epigenome editing.
Molecular biology: DNA methylation and chromatin profiling. Chromosome conformation capture
We are looking for independent researchers with strong communication skills, are open minded, and generous with their colleagues. A strong computational background is required. Familiarity with molecular genetics and mammalian cell culture would be helpful, but is not required.
The position is open in the recently formed team which is generously supported by an ERC Starting Grant to carry out studies of Chromatin Dynamics in Mammalian Development.
The research is carried out within the Institut Jacques Monod, which is a joint CNRS - Université de Paris research unit with approximately 350 employees. The IJM is part of the INSB and is housed in a recently constructed University building on the Paris Left Bank campus located in the 13th arrondissement of Paris and accessible by all means of transport (Metro 14, RER C, T3 tramway, bus 62 and 89...)
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