Ingénieur de recherche (M/F)
New
- Researcher in FTC
- 12 mounth
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut de Chimie Organique et Analytique
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
45067 ORLEANS
Contract Duration
12 mounth
Date of Hire
01/09/2026
Remuneration
3143€ brut per month
Apply Application Deadline : 08 June 2026 23:59
Job Description
Missions
The postdoctoral researcher's objective in this project will be (i) to synthesize new, more affinity- and selective ligands of the 5HT7 receptor by leveraging the reactivity of heteroaromatic rings (substitutions, metallocatalyzed coupling reactions, etc.) and (ii) to optimize the ADMET properties of the lead molecule. The synthesis of the target molecules and their precursors will utilize a variety of purification and analytical techniques (chromatography, precipitation, NMR, IR, LC/MS, HRMS, etc.).
Activity
- Perform multistep synthesis of organic molecules capable of binding to the 5-HT7 receptor. - Purify the molecules for evaluation in biological media. - Carry out complete structural characterization of these molecules (NMR, HRMS, pf, etc.). - Present results weekly to the team and quarterly to consortium members. - Write a final activity report including all experimental results.
Your Profil
Skills
The candidate must hold a PhD in organic chemistry with excellent theoretical and practical knowledge of organic chemistry. Standard purification and analytical techniques must also be well mastered (flash chromatography, NMR, HRMS, IR, etc.).
The candidate should be able to interact in a multicultural environment, as the team is involved in programs such as Erasmus and PHC (Hubert Curien Partnerships).
Your Work Environment
The research project will take place at the University of Orléans, within the Institute of Organic and Analytical Chemistry, in the Heterocyclic Chemistry – Bioactive Molecules and Fluorescent Probes research team.
The project will be supported by the institute's infrastructures (HRMS, 250 MHz and 400 MHz NMR, analysis/purification platform).
The candidate's work will be supervised on a daily basis by Prof. Franck Suzenet, Dr. Marie-Aude Hiebel, and Dr. Paul Demay-Drouhard.
The progress of the project will also be evaluated during weekly group seminars and through biannual meetings with the entire consortium.
Constraints and risks
Nothing
Compensation and benefits
Compensation
3143€ brut per month
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR7311-FRASUZ-003 |
|---|---|
| CN Section(s) / Research Area | Chemistry of and for life: design and properties of molecules of biological interest |
| Relevant experience | 1 to 4 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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