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Reference : UMR7285-FRAJER-003
Workplace : POITIERS
Date of publication : Sunday, October 10, 2021
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 January 2022
Proportion of work : Full time
Remuneration : 2663.79 à 3783.24 € according to experience
Desired level of education : PhD
Experience required : 1 to 4 years
Amines are a versatile class of compounds widely used in industry for the manufacture of agricultural chemicals, solvents, polymers, etc... In this context, the direct amination (hydroamination or hydroaminoalkylation) of cheap and industrially available alkenes (eg. octene, dodecene, etc…) is the royal way to synthetize alkyl amines in a one-pot and in a 100% atom economical fashion. Despite there exist a plethora of articles on the hydroamination or hydroaminoalkylation of alkenes, most of examples are restricted to activated alkenes (i.e featuring ring strain, conjugation, or substitution with electron withdrawing groups).
In this context, and on the continuation of previous investigations conducted at IC2MP, the objective of this position is to develop a metal-free catalytic system capable of coupling non activated alkenes with simple primary and secondary amines. The case of NH3 as an amination agent will be of particular interest as it is the simplest and the most abundant amine. This work will be conducted in partnership with the international joint unit CNRS/SOLVAY based at Shanghai (China) which will assist the candidate with its expertise in DFT calculations.
She/He will have in charge to develop the catalytic amination of non-activated alkenes with amines. Reactions will be typically performed in an autoclave and the reaction will be monitored by gas chromatography and 1H/13C NMR. She/He will also have to benchmark her/his results with the literature in terms of catalytic performances (yield, selectivity, productivity, etc.). The amination of 1-octene with dimethylamine will be first considered as a model reaction before considering the more challenging amination of long chain alkenes with ammonia.
strong knowledge in the field of catalysis (homogeneous or heterogeneous) applied to organic chemistry will be required. We are also expected the candidate to be curious and imaginative to challenge the team by proposing radically different approach. The candidate will also regularly interact in English by visio with the international joint unit CNRS/SOLVAY based at Shanghai
At the CNRS, these researches will be conducted at the Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP) located at the University of Poitiers in France. IC2MP is a joint unit between the University of Poitiers and the CNRS working on the design of sustainable reactions/products. This is an interdisciplinary institute investigating (1) the design of clean processes (catalysis, bio-solvents, renewables, alternative technologies, etc.) and (2) the transfer and bioaccumulation of organic molecules in eco-systems. In this project the candidate will join the team « Catalysis in unconventional media ». The team is conducting researches on (1) the replacement of fossil carbon by renewable carbon and (2) the development of clean technology for chemistry. The candidate will have a full access to the analytical platform of IC2MP (PLATINA), including all the major equipment required to characterize organic molecules and catalysts generated within this project (XPS, XRD, TEM/SEM, mass spectrometry, NMR, etc.).
This work will be supervised by IC2MP and co-supervized by E2P2L, a CNRS/SOLVAY joint unit.
Constraints and risks
Classical chemical risk exposure.Mission in France and abroad
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