General information
Offer title : Researcher (M/F) : Regulators of self antigen expression in the thymus (H/F)
Reference : UMR7280-MAGIRL-004
Number of position : 1
Workplace : MARSEILLE 09
Date of publication : 04 October 2024
Type of Contract : FTC Scientist
Contract Period : 3 months
Expected date of employment : 1 January 2025
Proportion of work : Full time
Remuneration : 3081-4166 euros
Desired level of education : Niveau 8 - (Doctorat)
Experience required : 1 to 4 years
Section(s) CN : Host-pathogen relationship, immunology, inflammation
Missions
Develop the “Regulators of self antigen expression in the thymus” project, which aims to characterize the role of the TCF7 transcription factor in the establishment of immune tolerance, in the team of Dr. Magali Irla.
Activities
- Design, implementation and execution of experiments.
- Analysis, validation and interpretation of results.
- Organize exchanges with collaborators involved in the project.
- Preparation of data for publication.
- Oral communication of the results.
Skills
- Expertise in T lymphocytes and thymic central tolerance.
- Multiparametric flow cytometry.
- Confocal microscopy.
- Molecular biology (scRNAseq approach).
- Animal experimentation and mouse models (autoimmunity).
Work Context
A mixed unit of the CNRS, INSERM and Aix-Marseille University, the CIML has around 200 staff and 14 research teams, and is located in the Luminy science and technology park in Marseille (France).
Constraints and risks
Product risk (CMR), biological agent risk, animal risk, work equipment risk, radiation risk, screen work risk.