Faites connaître cette offre !
Reference : UMR7275-HELMAR-002
Workplace : VALBONNE
Date of publication : Monday, May 03, 2021
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 June 2021
Proportion of work : Full time
Remuneration : between 2675 and 3805 euros according to experience
Desired level of education : PhD
Experience required : 1 to 4 years
In the context of the European project MILEDI funded by the FLAG-ERA HBP (https://miledi.lsmuni.lt), the research will focus on analyzing the acute impact of peptides cleaved from the amyloid precursor protein (APP) on neuronal function (synaptic plasticity and intrinsic excitability). The collected data will be used to study the peptides' effects with in silico modeling through the collaboration with our biophysics and mathematics MILEDI partners.
For this research, we will use pharmacology and in vivo viral expression of peptides coupled to field and patch-clamp electrophysiology on mouse brain slices (Willem et al Nature 2015; Pousinha et al, eLife 2017; Pousinha et al. Cell Reports 2019).
- expertise in patch-clamp electropysiology (if possible)
- expertise in scientific English necessary
- Level 1 certificate for animal experimentation (if possible)
- Skills in group work,in the piloting of research project
initial period of 2 years in the group of Dr. Hélène Marie & Jacques Barik at the Institut de Pharmacologie Moléculaire et Cellulaire (http://www.ipmc.cnrs.fr), Valbonne
We talk about it on Twitter!