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Reference : UMR7275-HELMAR-001
Workplace : VALBONNE
Date of publication : Monday, April 27, 2020
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 September 2020
Proportion of work : Full time
Remuneration : Between 2643 et 3766 euros before taxes depending on previous experience
Desired level of education : PhD
Experience required : Indifferent
In the context of the European project MILEDI funded by the FLAG-ERA HBP (https://miledi.lsmuni.lt), the research will focus on analyzing the acute impact of peptides cleaved from the amyloid precursor protein (APP) on neuronal function (synaptic plasticity and intrinsic excitability). The collected data will be used to study the peptides' effects with in silico modeling through the collaboration with our biophysics and mathematics MILEDI partners.
For this research, we will use pharmacology and in vivo viral expression of peptides coupled to field and patch-clamp electrophysiology on mouse brain slices (Willem et al Nature 2015; Pousinha et al, eLife 2017; Pousinha et al. Cell Reports 2019).
Highly motivated candidates holding a Ph.D. preferably with a background in neurosciences and expertise in whole-cell electrophysiology are encouraged to apply.
The candidate will work at the Institut de Pharmacologie Moléculaire et Cellulaire in Valbonne-Sophia Antipolis (Alpes Maritimes), France. The IPMC regroups 19 research teams and common services to host more than 220 staff. The candidate will work in the team of Drs Marie & Barik (Physiopathology of neuronal circuits and behavior).
For consideration, please send a CV, bibliography, a brief description of research experience and interests and the names of two references with telephone numbers and email addresses.
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