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Reference : UMR7265-NAJCOM-012
Workplace : MARSEILLE 09
Date of publication : Monday, July 20, 2020
Type of Contract : FTC Scientist
Contract Period : 23 months
Expected date of employment : 1 September 2020
Proportion of work : Full time
Remuneration : 2515 €
Desired level of education : PhD
Experience required : 1 to 4 years
We wish to appoint a highly motivated postdoctoral researcher to work within the ANR Project G4PLAST on the molecular mechanisms of chloroplast stress signalling in Arabidopsis.
The signalling nucleotide guanosine tetra-phosphate (G4P) is found in the chloroplasts of plants and algae where it accumulates in response to abiotic stress (see review, Field, 2018). Recent studies from our team (Sugliani et al., 2016) and other teams suggest that G4P is a potent inhibitor of chloroplast gene expression in vivo, and can regulate chloroplast function to influence both the growth and the development of plants. However, little is currently known about how G4P is wired into eukaryotic signalling pathways, or how it may act to enhance fitness when plants or algae are exposed to environmental stress. The successful postdoctoral candidate will join the G4PLAST project and work with us towards deciphering the molecular mechanisms that control G4P metabolism during stress acclimation in Arabidopsis.
Field B (2018) Green magic: regulation of the chloroplast stress response by (p)ppGpp in plants and algae. Journal of Experimental Botany. Review. Link
Sugliani M, Abdelkefi H, Ke H, Bouveret E, Robaglia C, Caffarri S, Field B. (2016) An Ancient Bacterial Signaling Pathway Regulates Chloroplast Function to Influence Growth and Development in Arabidopsis. Plant Cell. 28:661-79 Link
The successful candidate will use plant molecular biology and biochemistry approaches to decipher the molecular mechanisms that control G4P metabolism during stress acclimation in Arabidopsis.
- A PhD in biological sciences
- A solid background in plant molecular biology, biochemistry and plant genetics is required. Cellular biology and microscopy experience would also be an advantage but are not essential.
- Candidates must demonstrate a strong capacity for scientific communication (oral and written).
The candidate will work will in the Luminy Plant Genetics and Biophysics (LGBP) team on the Luminy Science and Technology Campus in the Calanques National Park, Marseille, France. The LGBP is part of the Institute of Bioscience and Biotechnology of Aix-Marseille (BIAM), and institute of more than 100 personnel based on the CEA Cadarache site on the Luminy Campus (http://biam.cea.fr/drf/biam/). Research at the BIAM is focused on understanding the adaptation and acclimation of living organisms (plants, algae, and bacteria) to environmental constraints. The LGBP has excellent plant growth facilities, and is equipped for molecular biology, biochemistry and plant physiology. A state-of-the-art microscopy platform is present on campus, and extensive biochemistry, biophysics and metabolite analysis platforms are available at the CEA Cadarache site of BIAM.
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