M/F post-doct "Optofluidic-fiber platforms for for bio-detection using plasmonic fluorescence enhancement”

Job Description

Missions

In the frame of the joint-lab IRP-CNRS “FiberMed” between XLIM research institute and the Translational Biophotonics Laboratory (A*STAR Skin Research Labs, Singapore), we are developing novel biosensing probes based on (specially designed) optofluidic fibers associated with plasmonic nanotechnologies and novel biosensing strategies, with the aim of creating new diagnostic tools for liquid biopsy.
You will be in charge of:
- developing a new version of an optofluidic fiber optimized for plasmonic enhanced fluorescence (PEF),
- identifying optimal properties of functionalized plasmonic nanoparticles to enhance the PEF effect,
- characterizing and measuring the PEF enhancement of the developed fiber-probes,
- developing bio-detection methods for biomarkers in fluids, based on the use of bio-receptors (antibodies, DNA probes, etc.) and fluorescence spectroscopy,
- improving the biodetection performance of fiber-based optofluidic probes by enhancing plasmonic interactions (PFE).
You will be also in charge of co-supervising student interns, and of collaborating with our biologist collaborators involved in this multidisciplinary project.

Activity

- Improvement of biosensing performances through theoretical and experimental studies of the plasmonic interactions
- Plasmonic nano-functionalization of the optofluidic fibers and characterization of their biosensing performances.
- Realization of fluorescence spectroscopy measurements.

- Synthesis and dissemination of results
- Co-supervision of students
- Participation in project management

Your Profil

Skills

Knowledge
- Expertise in plasmonics
- Expertise in biodetection enhanced by plasmonic interactions
- Training in nanophotonics or photonics
- Experience in detecting biomarkers in fluids
Desired skills
- Knowledge of biodetection methods for proteins and nucleic acids using bioreceptors (antibodies, nucleic acid probes, etc.)
- Experience in fluorescence spectroscopy

Skills
- Autonomy
- Decision-making capacity/sense of initiative

Your Work Environment

This post-doc takes place within the framework of the FluoDiag project funded by the Nouvelle Aquitaine. The successful candidate will be attached to the XLIM research institute under the dual supervision of the CNRS and the University of Limoges. He (She) will join the “Phot-fibre” team in the “Fiber photonics and coherent photonic sources” axis. He (She) will collaborate with colleagues from A*STAR Singapore, the CAPTUR laboratory (Inserm, Limoges University Hospital, University of Limoges) and our industrial partner.
The position is located in a sector falling under the protection of scientific and technical potential (PPST), and therefore requires, in accordance with regulations, that your arrival be authorized by the competent authority of the MESR.

Compensation and benefits

Compensation

Between €3041.58 and €3467.33 gross per month

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions