Faites connaître cette offre !
Reference : UMR7249-THOCHA-002
Workplace : MARSEILLE 13
Date of publication : Tuesday, October 29, 2019
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 January 2020
Proportion of work : Full time
Remuneration : between 2500 and 3000 € according to professional experience
Desired level of education : PhD
Experience required : 1 to 4 years
Research program: The project aims at developing a photoacoustic imaging setup to non-invasively access neuronal activity at large depths (≳ 2 mm) in the mouse brain.
To provide a sufficient detection bandwidth and hence achieve quasi cellular resolution, the acoustic field will be optically detected using custom-made Fabry-Pérot cavities. Wide-field interrogation strategies will be investigated to yield the high temporal resolution required for neuronal activity imaging. We will apply these techniques to perform calcium imaging in mice.
The candidate will:
- build the imaging setup
- help to design and fabricate the Fabry-Pérot cavities
- perform proof-of-principle tests using phantom samples
- measure calcium activity in live mice
Candidates with a PhD in physics, optics, electrical engineering, neuroscience (with some experience in optical imaging) or any related field are encouraged to apply. As this project is tightly linked to its applications in biology, the candidates are expected to have a strong interest for neuroscience and biology.
Programming skills are essential (Matlab or Python). As they will be evolving in an international environment, the candidates must be fluent in English, and exhibit excellent communications capabilities (written and spoken).
The project will be carried out at the Fresnel Institute in Marseille, within the MOSAIC group. Gathering more than 40 people from around the world, this interdisciplinary group is working at the crossroad of physics and biology.
Collaborations: As dealing with advanced optical fabrication and neurobiology, this project will be carried out in close collaboration with other groups from Marseille (RCMO group at Fresnel Institute, Cossart group at Inmed).
Constraints and risks
More information in http://www.fresnel.fr/perso/chaigne/
We talk about it on Twitter!