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Reference : UMR7245-PHIGRE0-002
Workplace : PARIS 05
Date of publication : Thursday, July 30, 2020
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 September 2020
Proportion of work : Full time
Remuneration : Gross monthly salary: from € 2,728 to € 3,881 depending on experience
Desired level of education : 5-year university degree
Experience required : 1 to 4 years
A postdoctoral position is available in the team “Biochemistry of Microbial Interactions” (BIM) of the laboratory “Molecules of Communication and Adaptation of Microorganisms” (MCAM), UMR 7245 CNRS-National Museum of Natural History (MNHN), Paris. The research of the postdoctoral fellow is within the framework of a project, funded by the French funding agency ANR, which aims at deciphering the mode of action of an antimicrobial peptide.
postdoctoral fellow will be in charge of the development of genetic systems and the implementation of the genetic code expansion approach, in order to incorporate non-natural amino acids into the peptide of interest. His/her main tasks include: - design and construction of the genetic systems; - production and purification of the resulting peptide variants; - structural characterization of the peptides; - writing scientific reports and publications in English
To apply, the candidate should have completed his/her Ph.D recently (less than two years) in the domain of synthetic biology. Solid knowledge and experiences in microbiology and/or analytical chemistry for peptides are required. It will be an advantage if the candidate has experience in genetic manipulation of Streptomyces. The candidate is expected to have a good capacity for teamwork and to work on multidisciplinary projects.
The work will be conducted in the laboratory MCAM at the enter of Paris. The work will benefit from the multidisciplinary environment of the MCAM laboratory, whose research centres on the characterisation of chemical factors (secondary metabolites, peptides and proteins) and mechanisms that regulate the microbial interaction between them, with the environment or with their hosts. Particularly, the team BIM possesses the necessary expertise and develops multidisciplinary approaches, ranging from peptide chemistry, biochemistry, microbiology, genomics, metabolomics and imaging techniques. The team is equipped and/or has access to all required instruments (e.g. high-resolution mass spectrometry, NMR etc) for the project.
Constraints and risks
Interested candidate should send a CV, a full list of publication and the names of two referees to Dr. Yanyan Li (email@example.com) before 31 July 2020. The expecting starting date is 1st September 2020, initially for one year and renewable for another year
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