Missions

This project is part of the Horizon Europe RIA SenseApest research programme, which is dedicated to developing a powerful, portable analytical tool for the rapid, effective and non-invasive diagnosis of imported plants. This portable detection unit must be capable of reliably identifying pest-infected plants or plant products. As a partner in this European project, our team will be responsible for developing fluorescent sensors for use in this device, as well as evaluating the responsiveness of these systems to volatile organic compounds, particularly monoterpene alcohols and terpenoids. These compounds will be tested in collaboration with the CAMATES team (Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé CPEES, UMR7515, Dr Stéphane Le Calvé) in Strasbourg, as well as with several other partners from the SenseApest consortium. The research engineer will be responsible for experimental work, characterisations and preparing scientific reports. She/He will benefit from an international research environment.

Activités

Development of synthetic methods for fluorescent sensors for the detection of volatile organic compounds.
Experimental work and characterizations.
Scientific reports and publications in English.
A B2 level in English is required for this position.

Compétences

The candidate must have a PhD in organic chemistry. She/He must have a solid knowledge of organic synthesis and methodology. We are looking for a highly motivated individual to get involved in this exciting multidisciplinary project. The candidate must also have good communication skills for collaborative work and regular exchanges with several teams from the 11-team European consortium, as well as skills in report writing and presenting results.

Contexte de travail

The research engineer will work with the Bio(in)organic and Medicinal Chemistry (CBM) team (Laboratoire d'Innovation Moléculaires et Applications, UMR 7042 LIMA-CNRS). This team develops projects in redox medicinal chemistry to combat various human infections (parasitic or viral). The CBM team has also developed expertise in fluorophore chemistry and functional tools for applications in life sciences or analytical chemistry (e.g. click chemistry, ferroptosis, ABPP, fluorophores for derivatization of compounds of interest, ratiometric or fluorogenic fluorescent pH or redox sensors). The team is supported by a physicochemical research platform led by an IE. Alongside two CNRS research directors and one CNRS ITA, the group currently comprises four PhD students and postdoctoral researchers. The laboratory is located at the European School of Chemistry, Polymers and Materials (ECPM) in Strasbourg, France.
The researcher will collaborate with students and postdoctoral researchers under the guidance of the project leader, Dr M. Elhabiri. She/He will dedicate her/his research work to developing synthesis routes for efficient and responsive fluorescent sensors, collaborating with the CAMATES team on the analytical part.
The strengths of the CBM team lie in the team's complementary skills at the crossroad between chemistry, biochemistry and physico-chemistry, the diversity of the teams and the expertises that make up the LIMA unit, the team's and LIMA's international recognition, the numerous academic and industrial collaborations, and the team's activities in technological development, innovation and transfer.
Thanks to the training opportunities the team offers based on its expertise and know-how in the design, analysis, and applications of compounds of interest, the team is also attractive to young researchers wishing to apply for CR positions at the CNRS.

Le poste se situe dans un secteur relevant de la protection du potentiel scientifique et technique (PPST), et nécessite donc, conformément à la réglementation, que votre arrivée soit autorisée par l'autorité compétente du MESR.

Contraintes et risques

Standard safety rules for organic chemistry training.
Specific laboratory rules will be covered in the training.

Informations complémentaires

Applications must include the following: - A detailed CV, including at least two references, scientists or supervisors who can be contacted. - Master's degree grades and a cover letter. - A summary of no more than five pages describing previous research experience. All the requested files should be provided in a single PDF file.