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Reference : UMR7042-MOUELH-001
Workplace : STRASBOURG
Date of publication : Friday, September 04, 2020
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 November 2020
Proportion of work : Full time
Remuneration : from 2675 € gross monthly depending on the candidate's experience
Desired level of education : PhD
Experience required : 1 to 4 years
This project is part of a research program (ANR Flash COVID-19 funded by the région Hauts de France) dedicated to the search for a potential treatment for SARS-CoV-2 infection (COVID-19). This project is based on the development of synthetic methodologies to prepare a series of compounds that will be tested at the Pasteur Institute of Lille. The postdoctoral researcher will be in charge of the experimental work, the characterizations and the writing of scientific reports. He/she will benefit from an international research environment.
Development of new synthetic pathways for high-potential antiviral compounds
Experimental work and characterizations
Scientific reports and publications written in English.
The candidate should have a PhD in organic chemistry. He/she should have a strong knowledge of organic synthesis and methodologies, and knowledge of medicinal chemistry. We are looking for a highly motivated researcher who will be able to get involved in this high-potential and topical project. In addition, the candidate should have good communication skills (collaborative work with two teams in Lille), a good team spirit and skills in report writing and presentation of results.
The postdoctoral researcher will work in the "Bio(IN)organic and Medicinal Chemistry" team (UMR 7042 LIMA-CNRS). This team develops projects in redox medicinal chemistry to combat several infections in humans (parasitic and viral infections). The team is backed by a research platform in physico-chemistry supported by an IE engineer CNRS. In addition to 2 CNRS research directors and 1 CNRS engineer, the group includes about 5 PhD students and post-doctoral researchers. The laboratory is located at ECPM in Strasbourg, France.
The researcher will work with the students and postdoctoral fellows under the supervision of the project leader (Dr M. Elhabiri). His/her research work will be dedicated to the development of straightforward synthetic pathways to prepare compounds that will be tested at the Pasteur Institute of Lille for their activity against SARS-CoV-2 (COVID-19).
The strengths of the "Bio(IN)chimie organique et médicinale" team are based on complementary skills at the chemistry/enzymology/physico-chemistry interface, on the diversity of the teams and skills that make up the LIMA unit, on the international recognition of both the team and the LIMA, on the various academic and industrial collaborations and the development, innovation and technology transfer actions that the team undertakes.
The team is also attractive for future young researchers wishing to apply for tenure positions at CNRS thanks to the multiple training opportunities it offers on the basis of its expertise and know-how in terms of design, analysis and discovery of future drugs.
Constraints and risks
Usual safety rules for the practice of organic chemistry. Training in the specific rules of the laboratory will be provided.
The application should include the following elements:
- A detailed CV including at least two references, who may be contacted.
- Master 2 grades, and a cover letter.
- A summary of a maximum of 5 pages of past research experience,
in one single PDF file.
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