Bioinformatics Research Engineer (M/F)

Job Description

Missions

This position is part of the SuPRTryP project, supported by the PEPR BBEST program, which combines computational and experimental approaches to harness the diversity of yeasts and valorize agri-food byproducts through fermentation.
The successful candidate will be responsible for the structural and functional annotation of enzymatic functions in yeast genomes, and for interpreting these in terms of metabolic pathways of interest. These methods will be applied to a selection of several hundred yeast strains chosen by the project consortium.

Activity

- Predicting the ability of yeasts to produce metabolic compounds of interest based on their genomes.
- Structural and functional annotation of yeast genomes of interest
- Reconstruction of metabolic pathways corresponding to tryptophan derivatives and identification of the best strains capable of producing them

Your Profil

Skills

- Advanced knowledge of bioinformatics.
- Genome assembly and annotation.
- Molecular biology.
- Implementation and deployment of bioinformatics pipelines
- Knowledge of machine learning
- Expertise in structural and functional genome annotation.
- Programming (Python).

Your Work Environment

This position is part of the SuPRTryP project, supported by the PEPR BBEST program, which aims to develop sustainable biotechnological alternatives to petroleum-based chemical synthesis for the production of high-value-added metabolites such as melatonin and serotonin. The project is based on the analysis of yeast genomes, the development of fermentation processes using residual biomass, and a use case focused on the valorization of byproducts from vineyards and winemaking. The goal is to create a complete value chain, from microbial biodiversity to the transformation of waste into value-added products, using methods that can be transferred to other industries.

The successful candidate will be expected to integrate into the project by collaborating with the project's bioinformatics engineers and PhD students (IRISA laboratory, Biographs/Dyliss team), members of the GenOuest bioinformatics platform for computational tasks, and the consortium's partner biologists and chemists.
The candidate will also be expected to participate in the annual PEPR BBEST events to share their achievements with all PEPR projects.

About the Laboratory
=============www.irisa.fr IRISA is now one of France's largest research laboratories (with over 850 staff) in the field of computer science and information technology. Organised into seven scientific departments, IRISA is a centre of excellence whose scientific priorities are bioinformatics, systems security, new software architectures, virtual reality, big data analysis and artificial intelligence. With its focus on the future of computing and an inherently international outlook, IRISA lies at the very heart of society's digital transition and of innovation in the fields of cybersecurity, health, the environment and ecology, transport, robotics, energy, culture and artificial intelligence. Information on the CNRS as an employer: https://www.cnrs.fr/fr/le-cnrs Information on IRISA as the host laboratory: https://www.irisa.fr/umr-6074 The post falls within a sector subject to the protection of scientific and technical potential (PPST) and therefore, in accordance with regulations, requires your appointment to be authorised by the relevant authority at the Ministry of Higher Education and Research (MESR).

Compensation and benefits

Compensation

From 2,496.98€ to 3,706.14€, depending on experience

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions