En poursuivant votre navigation sur ce site, vous acceptez le dépôt de cookies dans votre navigateur. (En savoir plus)
Portail > Offres > Offre UMR5306-RODANT-003 - H/F CDD 24 m Spectrométrie de masse sur virus et bactéries

M/F postdoctoral position :Mass Spectrometry of viruses and bacteria

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : vendredi 1 octobre 2021

Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler. Les informations de votre profil complètent celles associées à chaque candidature. Afin d’augmenter votre visibilité sur notre Portail Emploi et ainsi permettre aux recruteurs de consulter votre profil candidat, vous avez la possibilité de déposer votre CV dans notre CVThèque en un clic !

Faites connaître cette offre !

General information

Reference : UMR5306-RODANT-003
Workplace : VILLEURBANNE
Date of publication : Friday, September 10, 2021
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 3 January 2022
Proportion of work : Full time
Remuneration : between 2150 and 3069€ net monthly depending on experience and excluding withholding tax
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

A postdoctoral position is open at the “Institut Lumière Matière” in Lyon, France (iLM - Université Claude Bernard Lyon 1, CNRS) in the frame of the European project FET-OPEN ARIADNE “Redefining mass spectrometry – a breakthrough platform for real-time noninvasive breath analysis with single ion detection of intact viruses and bacteria and post-analysis molecular characterization” (see https://cordis.europa.eu/project/id/964553). The objective of the ARIADNE project is to develop a multiple-stage analytical platform based on multi-dimensional mass spectrometry instrumentation, and to perform direct and instant detection of intact virus particles in breath and in water. ARIADNE integrates state-of-the-art technological advancements in breath sampling and post-ionization methods as well as non-destructive ultra-high mass analysis of single bioparticles.

Activities

The postdoc hired at iLM-CNRS will be in charge of using our local expertise in charge detection mass spectrometry (CDMS) of large bioparticles. He/she will be responsible for the development and evaluation of the second generation CDMS system operated in stand-alone mode, analyzing viruses and bacteria using electrospray. Additional top-down analysis on single bioparticles will be executed in the CDMS system by multiphoton dissociation using a CO2 laser for producing high mass fragments.

Skills

The candidate should have a PhD in Physical-Chemistry or (Bio/Analytical)-Chemistry. He/she should be experienced in laser spectroscopy (action spectroscopy) and MS, in particular MS of protein complexes: an expertise in native-MS will be particularly appreciated. Experience in MS instrumentation is a significant plus. The candidate should be comfortable with biological (large proteins and assemblies) sample handling: purification, storage and preparation for native-MS and have a critical eye on the evaluation of the structural integrity of the systems.

Work Context

A Research Institute at the LyonTech–la Doua campus

Joint research laboratory of the Université Claude Bernard Lyon 1 and the CNRS (UMR5306)
Located on the LyonTech-la Doua campus at the heart of the Greater Lyon Metropole and the Auvergne Rhône-Alpes region
Over 300 students, research, teaching and support staff
6 research themes

Excellence in Physics and Chemistry Research:

Light for shaping and characterising matter
Fabricating (nano)materials and studying their optical, electrical, mechanical, thermal and rheological properties
Experimental and theoretical multi-scale methods : from nanometer to meter length-scales; from attosecond to second time-scales
Interdisciplinary projects in Engineering, Biological, Health and Environmental Sciences

Constraints and risks

laser safety and aerosols.

Additional Information

FP7 FET-OPEN
https://cordis.europa.eu/project/id/964553

We talk about it on Twitter!