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Portail > Offres > Offre UMR5305-JERSOH-004 - Chercheur H/F post- doctorant biomatériaux: développement d'oscillateurs biomimétiques de la corde vocale

Postdoctoral fellow : development of vocal fold biomimetic oscillators

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR5305-JERSOH-004
Workplace : LYON 07
Date of publication : Tuesday, November 20, 2018
Type of Contract : FTC Scientist
Contract Period : 18 months
Expected date of employment : 14 January 2019
Proportion of work : Full time
Remuneration : 2555.39 gross/month
Desired level of education : PhD
Experience required : 1 to 4 years

Missions

The postdoctoral fellow, hired for 18 months, will participate in the ANR Microvoice project, which aims to gain an in-depth understanding of the link between the micromechanics of vocal-fold tissues and their unique vibratory performances, and take the next step towards the development of new biomimetic oscillators.
He/she will develop new biomaterials mimicking the 3D fibrous architecture and micromechanics of the vocal-fold through the development of innovative hydrogels and their association with fibrous materials, and characterise the vibro-mechanical properties of these biomaterials at different scales and frequencies.
He/she will be part of the 'Skin function and dynamics' group at the laboratory of tissue biology and therapeutic engineering, which will relocate to the 'biological interactions and biomaterials' of MATEIS during the course of his/her project.
He/she will work within a 4/5-person group, under supervision of J. Sohier

Activities

Through an interdisciplinary background, the postdoctoral fellow will contribute to :
- design and develop novel biomaterials/fibrous architectures and composites mimicking the 3D fibrous architecture and micromechanics of the vocal-fold
- analyse the composite architecture through conventional and confocal/bi-photon microscopy and nanoscanner
- develop innovative bioactive hydrogels
- characterize the vibro-mechanical properties of the biomaterials at different scales and frequencies
- publish articles

Skills

- excellent academic training
- PhD in chemistry/biomaterials/formulation
- high quality publications
- experience and expertise of hydrogels and/or nanofibres will constitute an advantage
- Knowledge of microscopy technics (fluorescence, electron), X-ray-based imagery and in image and data analysis
- competences in mechanical characterisation of materials
- experience in cell culture optional but valued
- team-working in multidisciplinary projects
- aptitude to publish and present his/her results
- respect of ethics rules
- Imagination, creativity, enthusiasm, autonomy, organisational capacities, critical and synthetic set of mind
- good social skills and team spirit
- Excellent written and communication skills in English are required, while basic knowledge of French will be appreciated.

Work Context

The host team is currently part of the laboratory of tissue biology and therapeutic engineering (LBTI), in Lyon, France. The laboratory has a strong expertise in various soft tissues and aims to analyse the basic mechanisms of tissue organization and homeostasis, understand and model the tissue response to physiological or pathological stress and develop novel therapeutic approaches for tissue repair. The LBTI provides a highly multidisciplinary environment, gathering chemists, biochemists, cell and molecular biologists, bioinformaticians, physiologists, physicians and galenic experts. During the course of the project, the host team will relocate to MATEIS, which has a very extensive expertise in biomaterial development and characterization. The project will be performed in close collaboration with the 3SR laboratory in Grenoble, where top-level mechanical and vibratory analysis will be performed.

Constraints and risks

Relocation to a different laboratory during contract, in Lyon

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