General information
Offer title : Neuroscience Researcher 'Development and exploitation of protein-based biotechnological tools through directed evolution and protein engineering' M/F (H/F)
Reference : UMR5297-MELDES0-295
Number of position : 1
Workplace : BORDEAUX
Date of publication : 19 November 2025
Type of Contract : Researcher in FTC
Contract Period : 12 months
Expected date of employment : 1 January 2026
Proportion of work : Full Time
Remuneration : Between €3,041 and €3,467 gross monthly depending on experience
Desired level of education : Doctorate
Experience required : Indifferent
Section(s) CN : 25 - Molecular and cellular neurobiology, neurophysiology
Missions
Development and exploitation of protein-based biotechnological tools through directed evolution and protein engineering in the context of studying the molecular mechanisms of synaptic transmission.
Activities
Design of evolution strategies mainly guided by phage display. Implementation of strategies (creation of banks, screening, selection, etc.) for the selection of clones with the desired properties. Establishment of methods for validating isolated clones using biochemical, biophysical and cellular imaging methods. Engineering of protein tools using chemical or genetic methods.
Supervision and training. Writing articles.
Skills
General knowledge of chemistry and biology, basic concepts in mathematics, statistics and physics. Health and safety rules relating to the handling of toxic products, contaminants and genetically modified organisms (GMOs), The scientific field of structure, Mastery of experimental biology techniques, Knowledge of the principles and use of specific equipment in the field: incubators, spectrophotometers, thermocyclers, plate washers, microscopes, HPLC, SPR, ITC, etc. Using IT tools for data recording and equipment control. Communicating and managing relationships with internal and external contacts. Drafting technical procedures. Methodological and technological monitoring. Development and optimisation of methods and protocols.
Work Context
Created on 1 January 2011, the Interdisciplinary Institute for Neuroscience (IINS) is a joint research unit affiliated with the CNRS and the University of Bordeaux. With 170 staff members divided into 12 teams, IINS combines multidisciplinary expertise to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus, IINS is one of the major players in the neuroscience community in Aquitaine.
Constraints and risks
Possibility of working staggered hours