Informations générales
Intitulé de l'offre : Neuroscience researcher 'Role of protocadherins in the development of olivocerebellar connections' M/F (H/F)
Référence : UMR5297-MELDES0-272
Nombre de Postes : 1
Lieu de travail : BORDEAUX
Date de publication : mercredi 25 juin 2025
Type de contrat : Chercheur en contrat CDD
Durée du contrat : 6 mois
Date d'embauche prévue : 1 octobre 2025
Quotité de travail : Complet
Rémunération : From €2991.58 to €3417.33 gross per month depending on experience
Niveau d'études souhaité : Doctorat
Expérience souhaitée : Indifférent
Section(s) CN : 25 - Neurobiologie moléculaire et cellulaire, neurophysiologie
Missions
The researcher will study the role of protocadherin cell adhesion proteins in the development of olivocerebellar connections. To achieve this objective, he/she will use a hindbrain explant model and manipulate the expression of these proteins in individual neurons using the single-cell electroporation technique. The impact of these manipulations will be studied using electrophysiological, imaging and in situ hybridization approaches.
Activités
The candidate will carry out electrophysiology and imaging experiments in mouse brain explants. He/she will analyse the data, take part in formatting them into articles and present the results at national/international conferences.
Compétences
Hindbrain explant preparation, microscopy, electrophysiology (patch-clamp), keen interest in cellular and molecular neurobiology. Fluency in English (spoken and written) is essential.
Contexte de travail
Created on 1 January 2011, the Institut interdisciplinaire de neurosciences (IINS) is a joint research unit attached to the CNRS and the University of Bordeaux.
With 160 staff working in 14 teams, IINS combines multidisciplinary skills to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus, IINS is one of the major players in the neuroscience community in Aquitaine.
Contraintes et risques
Possibility of working shifts