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Portail > Offres > Offre UMR5297-MELDES0-136 - Chercheur post-doctorant "Etude des déformations et des réorganisations à l'échelle nanométrique de protéines individuelles à l'intérieur de structures mécanosensibles"" H/F

Post-doctoral researcher "Study of deformations and reorganizations at the nanoscale of individual proteins inside mechanosensitive structures" M/F

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : jeudi 8 décembre 2022

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General information

Reference : UMR5297-MELDES0-136
Workplace : BORDEAUX
Date of publication : Thursday, November 17, 2022
Type of Contract : FTC Scientist
Contract Period : 12 months
Expected date of employment : 1 January 2023
Proportion of work : Full time
Remuneration : Between 2805.35€ and 3224.81€ gross monthly depending on experience
Desired level of education : PhD
Experience required : Indifferent

Missions

Use of a cell stretching device compatible with super-resolution microscopy to study the deformations and reorganizations at the nanoscale of individual proteins within mechanosensitive structures, such as integrin-dependent adhesions, the cytoskeleton (actin, intermediate filaments). This scientist will also explore the mechanical responses (structural and functional) of mitochondria.

Activities

Conduct experiments documented in cell biology, protein biochemistry and molecular biology techniques to understand the organization of mechanosensitive structures.
Image acquisition in super-resolution microscopy and image analysis by computer.

Skills

Strong background in scientific computing and data analysis, and a deep interest in neuroscience and cell biology at the molecular and cellular level. He/she should also be familiar with super-resolution imaging and cell stretching techniques. The candidate should have a PhD in neuroscience or cell biology and have good oral and written communication skills in English.

Work Context

Created on January 1, 2011, the Interdisciplinary Institute of Neuroscience (IINS) is a joint research unit attached to the CNRS and the University of Bordeaux.
With 160 people in 14 teams, IINS combines multidisciplinary skills to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As a component of Bordeaux Neurocampus, IINS is one of the major actors of the neuroscience community in Aquitaine.

Constraints and risks

Possibility of working shifts

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