Postdoctoral fellow in chemical biology and supramolecular chemistry M/F
New
- Researcher in FTC
- 12 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Département de Chimie Moléculaire
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
38058 ST MARTIN D HERES
Contract Duration
12 months
Date of Hire
01/01/2027
Remuneration
Gross salary from €3041 depending on experience
Apply Application Deadline : 12 October 2026 23:59
Job Description
Missions
This project lies at the intersection of chemobiology and supramolecular chemistry. By using solid-phase DNA synthesis with non-natural molecular building blocks, the goal of this project is to create sequence-controlled DNA amphiphiles with sequence-controlled self-assembly properties.
These structures will be characterized using physicochemical methods (MS, NMR, DLS, AFM, etc.) and then used for the controlled delivery of therapeutic nucleic acids (antisense oligonucleotides, siRNA) in cellular models.
Activity
- Automated solid-phase synthesis of DNA, purification (HPLC, SPE), and characterization (HPLC, electrophoresis, MS)
- Organic synthesis of phosphoramidites (reactions under inert atmosphere, purification by chromatography)
- Physicochemical characterizations (NMR, DLS, MS, etc.)
- Biological assays (flow cytometry, qPCR, Western blot, etc.)
- Presenting results at meetings, writing publications
Your Profil
Skills
- Experience in oligonucleotide chemistry or in supramolecular and organic chemistry
- Experience in cell culture is preferred
- Ability to work as part of a team and communicate effectively
- Strong scientific rigor and organizational skills
- Minimum B2 level of English
Your Work Environment
The successful candidate for this position will join the Department of Molecular Chemistry (DCM). The DCM is a joint research unit (UMR 5250) involving the CNRS and the University of Grenoble Alpes. Currently, the DCM employs approximately 150 people whose scientific research focuses on major societal issues—such as health and well-being and new energy sources—while also addressing fundamental aspects of chemistry.
This position is funded for 12 months by the French National Research Agency (ANR JCJC SANTAC).
Compensation and benefits
Compensation
Gross salary from €3041 depending on experience
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5250-QUELAU-003 |
|---|---|
| CN Section(s) / Research Area | Chemistry of and for life: design and properties of molecules of biological interest |
| Relevant experience | 1 to 4 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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