En poursuivant votre navigation sur ce site, vous acceptez le dépôt de cookies dans votre navigateur. (En savoir plus)
Portail > Offres > Offre UMR5248-PIEMAI-001 - Post-doc (H/F) en biologie structurale de récepteurs couplés à une kinase.

Post-doc (M/W) in structural biology of protein kinase receptors.

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mercredi 1 juin 2022

Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler. Les informations de votre profil complètent celles associées à chaque candidature. Afin d’augmenter votre visibilité sur notre Portail Emploi et ainsi permettre aux recruteurs de consulter votre profil candidat, vous avez la possibilité de déposer votre CV dans notre CVThèque en un clic !

General information

Reference : UMR5248-PIEMAI-001
Workplace : PESSAC
Date of publication : Tuesday, April 26, 2022
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 October 2022
Proportion of work : Full time
Remuneration : €2 663,79 / €3 069.06
Desired level of education : PhD
Experience required : 1 to 4 years


The candidate will join the newly established team of Dr. Maisonneuve at the European Institute of Chemistry and Biology (IECB) to investigate the structural basis of the regulation of protein kinases and pseudokinases receptors in human signaling by using cryo-EM.


- Molecular biology (design and conception of plasmids for protein expression).
- Protein expression in eukaryotic cells (insect and human cells)
- Purification of membrane proteins
- Structural characterization of membrane proteins by cryo-EM.
- Functional and biophysical characterization of proteins in vitro and in cells (enzymology, ITC, Fluorescence polarization)


- Expertise in protein biochemistry (ideally in membrane proteins)
- Single-particle electron microscopy (cryo-EM)
- Protein expression in eukaryotic cells (insect and human)
- Ability to work independently and as a team member.
- Use of detergents, lipids, nanodiscs and amphipols.

Work Context

The candidate will join an exciting and multidisciplinary scientific environment with on-site access to cutting-edge facilities in cryo-EM (housing a 200kV Arctica equipped with a K2 summit camera and soon to come 200kV Cryo-electron microscope equipped with an energy filter and last generation direct detector), X-Ray crystallography, NMR, Biochemistry, Biophysics, molecular biology, and cell biology. The project involved international collaborations with biologists for complementary characterization of protein function in cells and in mice.

Constraints and risks


Additional Information

The position is funded for 2 years, but the candidate is encouraged to apply for additional postdoctoral funding.
Interested applicants should submit a cover letter, CV and contact information of 2 references

We talk about it on Twitter!