Missions

In the frame of granted ANR (French National Research Agency) project the candidate would work on the structure determination of partners of T9 secretion system using single particle cryoEM. He will develop method for stabilizing these complexes in membrane mimetic system, for optimizing cryoem grids, collect high resolution data and use image processing software to determine 3D reconstruction.
The project is within the framework of an ANR research program and will be conducted in collaboration with the groups of Philippe Leone (Institut de Microbiologie de la Méditerranée, Marseille), Eric Cascales (IMM, Marseille).

Activités

The successful candidate will join our group at the institute of Chimie et Biology des Membranes et Nano-objets (Pessac, Bordeaux) which aims at deciphering the molecular mechanisms of active transport across biological membranes, using biochemical, biophysical and cryoEM approaches.

Compétences

We are looking for a motivated and ambitious individual with a Ph.D. degree in biochemistry or biophysics. Experience in biochemistry and Membrane reconstitution, electron microscopy is essential; experience with membrane protein expression, and purification is preferred. Applicants should be able to take initiatives and responsibility within the work environment

Contexte de travail

The position is for 10 months and will be filled as soon as possible. The applicant should not have more than 2 years of experience after having completed his/her PhD. The salary will follow the CNRS guidelines.

Le poste se situe dans un secteur relevant de la protection du potentiel scientifique et technique (PPST), et nécessite donc, conformément à la réglementation, que votre arrivée soit autorisée par l'autorité compétente du MESR.

Contraintes et risques

Possible travels during the contract to other laboratories.