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Portail > Offres > Offre UMR5247-ANTMAR-002 - Post-doctorat en synthèse organique et chimie des nanoparticules (H/F)

Pos-doctoral position in organic synthesis and nanoparticle chemistry

This offer is available in the following languages:
Français - Anglais

Date Limite Candidature : mercredi 8 février 2023

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General information

Reference : UMR5247-ANTMAR-002
Nombre de Postes : 1
Workplace : MONTPELLIER
Date of publication : Wednesday, January 18, 2023
Type of Contract : FTC Scientist
Contract Period : 18 months
Expected date of employment : 8 February 2023
Proportion of work : Full time
Remuneration : 2833
Desired level of education : PhD
Experience required : Indifferent

Missions

In collaboration with a team of biologists, we are developing new therapeutic approaches to combat chemoresistance in cancers. In this context, we are recruiting an organic chemist to lead the design and synthesis of hybrid organic-inorganic nanostructures featuring anticancer properties. Thus, the core of the project will concern the synthesis of organic oncoprotein ligands (to be set up or reproduced). A second crucial aspect of the project will concern the chemistry of nanoparticles (mainly silica) and their functionalization by previously prepared organic molecules. The involvement of the post-doctoral fellow in transdisciplinary meetings with our biologists, the interpretation of the data and their valorization (communication, publication or patent) will also be required.

Activities

Research, design and develop chemical synthesis techniques.
Participate in the development and management of the project
Choose the appropriate synthesis techniques; develop adequate procedures.
Perform routine characterization of the products
Validate data and interpret results
Valorization of the results: writing reports and publications
Continuous monitoring of the scientific literature concerning the project.
Train and inform about the risks related to the techniques and products

Skills

Organic Chemistry (in-depth knowledge) and Sol-gel chemistry (in-depth knowledge)
Chemical synthesis methods (in-depth knowledge)
Chemical analysis techniques (general knowledge)
Chemical species (general knowledge)
Chemical risks and their prevention

Work Context

Biomolecules are complex organic molecules (composed of carbon and hydrogen, but also oxygen, nitrogen, sulfur, etc.) that are found only in the living world, since they are formed by the organism itself. These are, for example, molecules such as DNA, RNA, proteins, sugars, lipids... The Max Mousseron Institute of Biomolecules (IBMM or UMR5247 CNRS-Université Montpellier), whose director is Professor Pascal Dumy, is an international research institution and one of the 4 founding institutes of the Balard Chemistry Pole of Montpellier. Research activities focus on essential biomolecules such as lipids, nucleosides, nucleotides and nucleic acids, peptides and proteins, glycosides, biopolymers, prebiotic molecules and fluorinated molecules. The research programs conducted around biomolecules concern their design, synthesis and pharmacology. These biomolecules and their families of compounds are used as basic molecules in pharmacology for the study of physiological and pathological mechanisms associated with them, they are also the essential molecules precursors of future drugs. IBMM's research activities are located at the interface of chemistry and biology, they aim to study and understand the mechanisms of action of biomolecules and the treatment of human and animal pathologies (infectious, cardiovascular, degenerative, cancer...) with applications in the molecular medicine of tomorrow. At the same time, these biomolecules are intended to be used in wide fields of application such as cosmetology, agriculture, agronomy and the veterinary industry which respect the environment and are part of sustainable development (green chemistry). The recruited postdoctoral fellow will conduct their research activities in the Department of Amino Acids, Peptides and Proteins: https://ibmmpeptide.com/

Constraints and risks

Chemicals will be handled according to the rules of the H&S officer.

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