Reference : UMR5239-MIRFRA-004
Workplace : LYON 07
Date of publication : Wednesday, May 4, 2022
Type of Contract : FTC Technical / Administrative
Contract Period : 12 months
Expected date of employment : 1 June 2022
Proportion of work : Full time
Remuneration : between 1967 et 2100 € gross monthly, according to experience
Desired level of education : 2-year university degree
Experience required : 1 to 4 years
The Quantitative Regulatory Genomics team lead by Mirko Francesconi at LBMC Lyon received funding from ANR to understand which molecular and phenotypic differences are induced by parental environment and what is the mechanism of signal transmission and interpretation across generations.
The appointee will provide support in running the lab and carry out experimental work to dissect molecular requirements of signal transmission and interpretation.
- Managing lab databases, ordering reagents and preparing solutions, ensure maintenance of stocks, consumables and equipment
- Perform experiments with C. elegans (crossing, phenotyping…)
- Help developing an optogenetic tool in C. elegans (in collaboration with Gael Yvert team)
- Good level of spoken and written English
- Experience of working in a biology research laboratory
- Experience of lab housekeeping (ordering, health and safety, etc)
- Knowledge of laboratory procedures, materials, equipment
- Good team-working and cooperative spirit
- Ability to organise and prioritise own workload
- Fast learning
- Experience with C. elegans (basic maintenance and handling, RNAi by feeding)
- Experience with microscope-based phenotyping and screening
The LBMC aims to characterise the molecular bases underlying the organisation and functioning of cellular processes in normal and pathological conditions. The laboratory develops genetic and quantitative analyses of biological systems, systems biology and modelling approaches. Teams strive to integrate different aspects of cellular life: cell division, architecture, proliferation and differentiation, tissue integration, regulation of gene expression, epigenetics, structure and interaction of biomolecules
The broad interest of the team is understanding how genetic, epigenetic and environmental factors and their interplay impact on gene regulation in space and time, to generate phenotypic variation. To this end we use both computational and experimental approaches in metazoans.
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