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Portal > Offres > Offre UMR5239-MIRFRA-001 - Assistant de recherche en Biologie (H/F)

Technician / Lab manager

This offer is available in the following languages:
Français - Anglais

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General information

Reference : UMR5239-MIRFRA-001
Workplace : LYON 07
Date of publication : Thursday, July 16, 2020
Type of Contract : FTC Technical / Administrative
Contract Period : 18 months
Expected date of employment : 1 September 2020
Proportion of work : Full time
Remuneration : Salary: betweeen 1600 and 2000 € before taxes according to experience
Desired level of education : 3-year university degree
Experience required : 1 to 4 years

Missions

The broad interest of the Francesconi team is understanding how genetic, epigenetic and environmental factors and their interplay impact on gene regulation.
We have found that environmental perturbation in parental generation impacts the next generation of non-exposed individuals in the nematode C. elegans. We have recently received funding from ANR to understand which molecular and phenotypic differences are induced by parental environment and what is the mechanism of signal transmission and interpretation across generations.

The appointee will work on this project to understand the mechanisms of transmission and interpretation of environmental signals from one generation to the next.

Activities

- Set up and performing mutant screens and phenotyping for the molecular dissection of the transmission and interpretation of intergenerational signals.
- Test, calibrate and use a new C. elegans optogenetic switch (in collaboration with Gael Yvert's team) to test the specific cellular and time requirements of screen hits.

Associated activities

- daily management of the laboratory: participation in the management of orders (reagents, consumables) and laboratory equipment
- computer organization of scientific product stocks (antibodies, primers, chemicals, etc.) and research protocols.


Associated activities

- daily management of the laboratory: participation in the management of orders (reagents, consumables) and laboratory equipment
- computer organization of scientific product stocks (antibodies, primers, chemicals, etc.) and research protocols.

Activités associées

• gestion quotidienne du laboratoire : participation à la gestion des commandes (réactifs, consommables) et des équipements du laboratoire
• organisation informatique des stocks de produits scientifiques (anticorps, primers, produits chimiques, ....) et des protocoles de recherche.

Skills

- Knowledge of Good Laboratory Practice
- Fluency in English (reading and analysis of scientific publications, participation in team meetings, presentation of results)
- Knowledge of basic molecular biology techniques (PCR etc...)
- Knowledge of basic computer tools (Excel etc...)
- Organization and analysis of experimental data
- Maintaining a laboratory notebook


Desired experience

- Experience with C. elegans (basic handling)
- Experience with microscope phenotyping

Work Context

The LBMC is located on the ENS Monod campus, Gerland, Lyon.
LBMC's research aims to characterize the molecular bases of the functioning of living organisms.

The scientific mission of the Francesconi team is to understand how genetic, epigenetic and environmental factors and their interactions impact the regulation of genes in space and time to generate phenotypic variations. To this end we use both computational and experimental approaches in metazoans.

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