Faites connaître cette offre !
Reference : UMR5239-ISASER-005
Workplace : LYON 07
Date of publication : Tuesday, July 16, 2019
Type of Contract : FTC Scientist
Contract Period : 15 months
Expected date of employment : 1 October 2019
Proportion of work : Full time
Remuneration : 2 650 euros gross monthly
Desired level of education : PhD
Experience required : Indifferent
Study the molecular and cellular mechanisms involved in a meiotic drive system in the Drosophila male germline
The postdoc fellow will use classical genetic and cellular techniques such as DNA-FISH, IF, confocal microscopy to understand the mechnisms that result in elimination of abnormal sperm nuclei in Drosophila. She/he will work in close collaboration with a CNRS researcher
• Genetics with an experience on Drosophila melanogaster
• Molecular biology (cloning, PCR, RT-PCR, qPCR...)
• Cellular biology (immunofluorecence, DNA et RNA-FISH)
• Imaging (confocal microscopy)
• Ability to work in a team
The postdoc fellow will integrate the team entitled "Epigenetics and zygote formation" led by par Benjamin Loppin. Within LBMC, this team currently hosts four permanent researchers and a graduate student. Two main research axes are developped in this group : 1) the mechanisms involved in paternal chromosome integration to form a zygote at fertilization and 2) the mechanisms that shape the sperm nucleus. These projects use Drosophila melanogaster as a model organism and the cricket Gryllus bimaculatus.
Constraints and risks
: The "Laboratoire de Biologie et Modélisation Cellulaire" (LBMC) is a research institute located at the "Ecole Normale Supérieure de Lyon" in the Gerland neighborhood of Lyon and hosts fifteen research teams. This institute aims at characterizing the molecular bases underlying the organisation and functioning of cellular processes in normal and pathological conditions. The laboratory develops genetic and quantitative analyses of biological systems, systems biology and modelling approaches
We talk about it on Twitter!