General information
Offer title : Postdoctoral Researcher in molecular genetics (M/F) (H/F)
Reference : UMR5239-CHRCHA-003
Number of position : 1
Workplace : LYON 07
Date of publication : 28 August 2025
Type of Contract : Researcher in FTC
Contract Period : 12 months
Expected date of employment : 1 November 2025
Proportion of work : Full Time
Remuneration : 3021.5 euros to 3 451.51 euros monthly according to experience
Desired level of education : Doctorate
Experience required : Indifferent
Section(s) CN : 21 - Organisation, expression and evolution of genomes Bioinformatics and systems biology
Missions
The project aims to determine the molecular mechanism facilitating homology search during DNA break repair by homologous recombination.
Activities
Synthetic biology in S. cerevisiae: development and characterization of large designer synthetic chromosomal regions.
Omics approaches (Hi-C, ChIP-seq, etc.) and molecular approaches to determine the consequences of chromatin modifications on DNA break repair
Skills
Know-how.
Expertise in molecular genetics of S. cerevisiae yeast .
Expertise in omics methods.
. Preferred: ability to perform bioinformatic analyses
Interpersonal skills.
Independence.
Ability to work in a team and adapt to the needs of colleagues.
Creativity
Cross-functional skills.
Ability to learn new technologies/languages.
Bibliographic monitoring
Work Context
Located at the ENS in Lyon, in a rich multidisciplinary environment, the LBMC is an experimental biology laboratory whose object of study is the cell, the fundamental unit of life.
The 15 teams at the LBMC include in their research different aspects of cellular life such as proliferation, differentiation, and interaction with the cellular environment in a normal or pathological context. The fundamental research conducted at the laboratory draws on expertise in cellular and molecular biology and is resolutely interdisciplinary, integrating approaches in (bio)informatics, (bio)physics, and (bio)mathematics.
The “genome mechanics” team is interested in the process of DNA break repair by homologous recombination and its intersection with the spatial organization of chromatin in the nucleus. They use high-throughput genomics approaches in the model organism S. cerevisiae. They are looking for a motivated postdoctoral researcher.