Ingénieur d'études en microbiologie et génétique (M/F)
New
- Researcher in FTC
- 6 mounth
- Doctorate
Offer at a glance
The Unit
Laboratoire de Microbiologie et de Génétique Moléculaires
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
31062 TOULOUSE
Contract Duration
6 mounth
Date of Hire
01/07/2026
Remuneration
between 3041€ et 3467€ monthly- depending on experience
Apply Application Deadline : 30 March 2026 23:59
Job Description
Missions
The aim of the project is to characterise the mobile genetic elements that influence the synthesis, biochemistry or regulation of the extracellular capsule and how they can impact horizontal transfers in the enterobacterium Klebsiella pneumonia.
Activity
Identification and validation of genes influencing production of the capsule
1.1 Cloning of regulators and/or capsule synthesis genes in expression vectors
1.2 Quantification of the capsule (biochemically and microscope image analyses)
1.3 Quantification of horizontal transfer
Your Profil
Skills
Knowledge
Coding in R for data analysis, classical population microbiology techniques
Ability to generate mutants in Klebsiella pneumoniae
Ability to analyse genomic data, including the identification of different mobile genetic elements
Skills
Proficiency in English
Writing articles in English
Implementation and optimisation of molecular genetics protocols
Interpersonal skills
Interacting positively with team members, respect for others
Helping team members
Knowledge transfer
Your Work Environment
The project will be developed under the scientific direction of Olaya Rendueles (at CBI-Toulouse). It involves identifying and characterising the diversity of mobile genetic elements (MGEs) that modify the capsule. Using comparative genomics, we will screen MGEs for capsule genes and capsule regulatory elements, and identify common genomic signatures of capsule-modifying MGEs. We will then experimentally validate the impact of these MGEs on the capsule production of their host and test whether they act selfishly to limit the absorption of other MGEs, thereby restricting gene flow due to altered capsule production.
Compensation and benefits
Compensation
between 3041€ et 3467€ monthly- depending on experience
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5100-OLAREN-007 |
|---|---|
| CN Section(s) / Research Area | Organisation, expression and evolution of genomes Bioinformatics and systems biology |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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