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Reference : UMR5088-ARNBES-002
Workplace : TOULOUSE
Date of publication : Wednesday, January 15, 2020
Type of Contract : FTC Scientist
Contract Period : 6 months
Expected date of employment : 2 March 2020
Proportion of work : Full time
Remuneration : Between 2643 and 3017 € monthly gross salary depending on experience
Desired level of education : Higher than 5-year university degree
Experience required : 1 to 4 years
A postdoctoral position is available in the “Cell Cycle & Cancer” team at the Centre for Integrative Biology/LBCMCP UMR5088, in Toulouse, France (http://cbi-toulouse.fr/eng/equipe-cycle-cellulaire-et-cancer) for highly motivated and talented candidates interested in cell cycle control and stem cell biology.
The team is interested in deciphering the mechanisms by which the cell cycle machinery coordinates different cellular processes and how the deregulation of these mechanisms contributes to tumor development. This project aims at studying the role of the CDK inhibitor p57Kip2 in the regulation of intestinal stem cell fate and proliferation and to determine its role in intestinal tumor development.
The selected candidates will:
-participate in the conception of the project
-use and develop methodologies
-analyze and present data
-write research articles
The candidate will use a broad panel of approaches ranging from genetic to cell biology (imaging, cytometry, sorting, tissue culture) and molecular biology (ChIP-seq, co-IP, cloning…) on murine tissues, primary cells and cell lines.
Candidates (M/W) must hold a PhD and have strong skills in molecular and cellular biology. Expertise in genetics and/or cancer biology is also an asset. The candidate must have a strong publication record, be rigorous, and have strong organizational and teamwork skills. The candidate must be able to communicate in English (written/oral), knowledge of French is not mandatory. Although the initial contract is for 6 months, it is expected that the successful candidate will apply for a postdoctoral fellowship (with help from the team) for another 2 years of funding from external sources.
Founded in 2016, the Centre for Integrative Biology of Toulouse (CBI; http://cbi-toulouse.fr/eng/) is an institute regrouping five research centers in Biological Sciences of the University of Toulouse and the French National Centre for Scientific Research (CNRS). It is located in Toulouse, South West of France, in the main Campus of the Université Toulouse III-Paul Sabatier (http://www.univ-tlse3.fr/), which offers a multidisciplinary education in the fields of science, health, engineering, and technology, developing one of the most important scientific research clusters in France. In 2020, CBI will benefit from a brand new building currently in construction, in line with its expansion policy.
The CBI currently brings together more than 400 scientists in 40 research teams with worldwide recognition, aimed to foster research leading to the elucidation of fundamental aspects of the structure and function of complex biological systems, and covering all scales from individual molecules to the whole organism and population. Within a highly collaborative scientific environment, researchers have access to either in-house or nearby state-of-the art technological facilities, including photonic and electron microscopy, a computer cluster for large data analysis and simulation, animal facilities, deep sequencing and proteomics.
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