Researcher: Stretching and compression on the epithelial-mesenchymal transition under stress (M/F)
New
- Researcher in FTC
- 30 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Unité de biologie moléculaire, cellulaire et du développement
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
31062 TOULOUSE
Contract Duration
30 months
Date of Hire
01/12/2026
Remuneration
Between €4,216.70 and €4,395.65 gross, depending on experience
Apply Application Deadline : 02 October 2026 23:59
Job Description
Missions
The goal of this project is to explore the effects of mechanical forces on the cell nucleus during epithelial-mesenchymal transition (EMT), a critical cellular process that occurs in both physiological and cancerous contexts. The project will involve conducting experiments on Drosophila tissues.
Activity
- Characterize the cellular and nuclear dynamics of different types of EMT using high-resolution live-cell imaging and immunolabeling. These images will then be analyzed in 3D using automated methods.
- Manipulate the physical constraints to which nuclei are subjected and compare transcriptional dynamics.
- Explore the response to controlled forces.
Your Profil
Skills
- Expertise in developmental biology and in particular a good knowledge of drosophila and chicken models.
- Expertise in confocal microscopy, live imaging, image analysis and segmentation, immunostaining, molecular biology and electroporation.
Your Work Environment
Positioning of Magali SUZANNE's team within the MCD unit:
We are interested in the process of morphogenesis and seek to understand how organs acquire their specific shapes. We are more specifically interested in cellular dynamics during fundamental cellular events such as cell death or cell delamination and seek to characterize their impact on epithelial sheet remodeling. In addition to the biochemical signals that cells send to modulate the behavior of their neighbors, cells can also influence their environment mechanically. One of the key objectives of mechanobiology, a rapidly expanding field of research, is to understand how mechanical forces are generated, transmitted and integrated within a tissue.
Compensation and benefits
Compensation
Between €4,216.70 and €4,395.65 gross, depending on experience
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5077-MARPEL1-025 |
|---|---|
| CN Section(s) / Research Area | Molecular and structural biology, biochemistry |
| Relevant experience | 5 to 10 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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