Researcher in Biophysics (M/F)

Job Description

Missions

A study aimed at understanding the behavior of proteins within and on the surface of biomolecular condensates at the Galvanetto lab (https://galvanettolab.org/).

Activity

1. Carrying out research work, from setting up the experiment to writing up the results:
At least two of the following:
- Innovating smFRET methods to measure protein dynamics on the surface of biomolecular condensates.
- Analysis of smFRET data to study conformation and dynamics of disordered proteins in condensates.
- Expression and purification and labeling of intrinsically disordered proteins.
- Develop electrophysiology measurements to measure voltage within biomolecular condensates.

2. Participate in the life of the laboratory:
- Take part in the life of the research group (logistics, reagent stocks, tidying up, etc.)
- Help supervising trainees
- Take part in the Institute's scientific events

Your Profil

Skills

- Willingness to learn and operate at the edge of one's comfort zone is required.
- Expertise in single molecule methods is preferred.
- Expertise with custom optical microscopes is preferred.
- Expertise in data analysis and coding is highly preferred.
- Expertise in expression and purification and labeling of proteins is preferred.
- Knowledge of other biophysical methods for protein characterization.
- Rigor, intellectual curiosity, taste for teamwork.

Your Work Environment

Located on the Grenoble Science Park (ESRF/ILL/EMBL/IBS), the Institute of Structural Biology (IBS) is a national and international player in the field of integrated structural biology. The IBS is a research center, a technical platform, a host site and a scientific training center. Its mission is to develop research in structural biology, a field of research that is crucial to the understanding of fundamental biological mechanisms. It is supported by 12 state-of-the-art platforms.
As a joint research unit (CEA-CNRS-UGA), the IBS is composed of 20 research groups, each of which proposes a multi-disciplinary approach, at the frontiers of biology, physics and chemistry, in coherence with 3 research axes. Nearly 320 people work there as researchers, PhD students, engineers and technicians in a multicultural and international environment.
The person recruited will join the newly established Single-molecule Biophysics team run by Nicola Galvanetto (https://galvanettolab.org/), funded by the ATIP program and by the Ernst Hadorn Foundation, within the Protein Dynamics division led by Martin Blackledge.

Constraints and risks

Without.
The research will be carried out in english, however, non-French-speaking candidates are expected to make an effort to learn the basics of French in order to facilitate communication and their integration into the laboratory.

Compensation and benefits

Compensation

Between €3,041.58 and €4,216.70 (depending on experience)

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions