Post-doctoral fellowship in biochemistry/glycobiology – M/F
New
- Researcher in FTC
- 18 months
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut de biologie structurale
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
38044 GRENOBLE
Contract Duration
18 months
Date of Hire
01/01/2027
Remuneration
between 4216 € et 4395 € (according to experience)
Apply Application Deadline : 26 November 2026 23:59
Job Description
Missions
Study the structure and functional properties of a bacterial sulfatase targeting glycosaminoglycans. Generate and characterize mutants aimed at improving the enzyme's properties.
Activity
- Express and purify recombinant enzymes.
- Perform enzymatic activity assays and determine kinetic parameters.
- Develop protein design approaches to generate mutants with improved enzymatic properties.
- Validate the enzymatic properties of selected mutants.
- Determine the structures of selected mutants using X-ray crystallography.
- Present research findings at scientific congresses and conferences.
- Write activity reports and scientific publications.
Your Profil
Skills
- Expertise in recombinant protein production.
- Expertise in enzymology.
- In-depth knowledge of structural biology.
- In-depth knowledge of glycosaminoglycan (GAG) biology.
- English (written/oral) level B2 minimum
Your Work Environment
Located on the Grenoble Science Park (ESRF/ILL/EMBL/IBS), the Institute of Structural Biology (IBS) is a national and international player in the field of integrated structural biology. The IBS is a research center, a technical platform, a host site and a scientific training center. Its mission is to develop research in structural biology, a field of research that is crucial to the understanding of fundamental biological mechanisms. It is supported by 12 state-of-the-art platforms.
As a joint research unit (CEA-CNRS-UGA), the IBS is composed of 20 research groups, each of which proposes a multi-disciplinary approach, at the frontiers of biology, physics and chemistry, in coherence with 3 research axes. Nearly 320 people work there as researchers, PhD students, engineers and technicians in a multicultural and international environment.
The person recruited will join the SAGAG group working on glycosaminoglycans (https://www.ibs.fr/en/research/membrane-proteins-and-glycobiology/structure-and-activity-of-glycosaminoglycans-group-h-lortat-jacob/).
Constraints and risks
- Handling of human cells
The research will be carried out in either French or English, however it is expected that the non-French speaking candidate will strive to learn the basics of French in order to facilitate communication and integration into the laboratory.
Compensation and benefits
Compensation
between 4216 € et 4395 € (according to experience)
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR5075-CYNDAV-092 |
|---|---|
| CN Section(s) / Research Area | Molecular and structural biology, biochemistry |
| Relevant experience | 5 to 10 years |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
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