Missions

The successful candidate will work on the development of new NMR experiments to push the biological applications of NMR beyond their current limits, and apply the new methods to the study of large molecular complexes and machines of medical interest, as part of the the European ERC advanced grant XXL-NMR project.

Activities

- Development of NMR pulse-sequences
- Development advanced NMR processing schemes
- Programming and Simulation
- NMR characterization of large protein complexes
- Dynamics studies of large protein complexes
- Co-supervision of students
- Publication writing
- Taking part in the life of the research group (contributing to logistics, computers set-up, etc…)

Skills

- Candidates must hold a PhD in NMR spectroscopy, structural biology, biophysics or physical chemistry (or a related field).
- Expertise or interest in the development of NMR pulse sequences for solution or solid-state NMR will be appreciated.
- Ability to conceptualize, creativity, scientific curiosity, sense of innovation.
- Good communication (written/oral) and teaching skills.
- Team spirit.
- C2 level in English (written/oral)

Work Context

No particular risk.
All research-related exchanges will be in English. To facilitate communication with IBS administrative services and integration in France, the selected candidate will have the opportunity to take French courses.

Constraints and risks

Located on the Grenoble science campus (ESRF/ILL/EMBL/IBS), the structural biology institute (IBS) is a leading national and international research institute in the field of integrated structural biology. The IBS is a research center, a technical infrastructure, a host site and a scientific training center. Its mission is to develop research in structural biology, a crucial field for understanding fundamental biological mechanisms. It is supported by 12 state-of-the-art facilities, including high field NMR facility equipped with 950, 850, 700 and 600 MHz NMR spectrometers with liquid-state cryoprobes and advanced solid-state technologies.
As a joint research unit (CEA-CNRS-UGA), the IBS is made up of 20 research groups, each offering a multidisciplinary approach at the frontiers of biology, physics and chemistry, in line with the IBS's 3 main research axis. Nearly 300 people work at IBS as researchers, post-docs, PhD students, engineers and technicians in a multicultural and international environment.

The postdoctoral researcher recruited will join the NMR of Large Assemblies group, which develops and applies advanced isotope labelling and NMR methods to study the structure, dynamics and mechanisms of large protein complexes. The group headed by Dr. Boisbouvier comprises a research director, three engineers, two post-docs and two PhD students.