Missions

The successful candidate will conduct experimental research in the physico-chemistry of soft and biological matter, focusing on : Anisotropic Microgels by Controlled Assembly of Viral Particles in Microfluidic Droplets (ViroGel).

Activités

- Preparation, physico-chemical characterization, and functionalization of samples (microgels, phages, etc.)
- Video microscopy (fluorescence, dark-field, etc.)
- Dynamic light scattering (DLS)
- Small-angle X-ray scattering (SAXS)

Compétences

We are seeking a highly motivated candidate with a background in physico-chemistry or soft matter physics (or related fields). While not mandatory, expertise in colloidal liquid crystals or basic knowledge of microbiology for viral particle production and bioconjugation would be advantageous.
Essential requirements:
- Fluency in English
- Strong motivation for research
- Interest in working in an international and multidisciplinary environment

Contexte de travail

This position is part of the ViroGel project, an interdisciplinary initiative funded by the French National Research Agency (ANR). The project aims to uncover the physical principles governing the self-assembly and phase behavior of filamentous fd viral particles, confined within microfluidic droplets, and to exploit this understanding to create anisotropic, compartmentalized microgels with programmable structure. By investigating how confinement, interparticle interactions, phase separations, chemical functionalization and external parameters such as temperature, pH, and ionic strength regulate the ordering of viral particles—from dilute to liquid-crystalline phases— the project will investigate and ultimately control the emergence of size, shape, and internal morphology in these soft biological materials. The self-assembly properties of these virogels in aqueous solution will also be determined, along with their enzymatic modification, to explore their catalytic activity.

Le poste se situe dans un secteur relevant de la protection du potentiel scientifique et technique (PPST), et nécessite donc, conformément à la réglementation, que votre arrivée soit autorisée par l'autorité compétente du MESR.

Contraintes et risques

No specific risks identified.

Informations complémentaires

Applications should include: a CV, a detailed statement of interests for our research project, and contact information for 3 references.
For more information and related publications, visit:
https://www.crpp.cnrs.fr/eric-grelet/