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Reference : UMR2594-FABROU-001
Workplace : CASTANET TOLOSAN
Date of publication : Monday, July 19, 2021
Type of Contract : FTC Scientist
Contract Period : 36 months
Expected date of employment : 1 October 2021
Proportion of work : Full time
Remuneration : between 2530 and 3509 € gross monthly depending on experience
Desired level of education : PhD
Experience required : 1 to 4 years
Infectious disease is often the major selective agent in nature, and we cannot understand how populations evolve without understanding their pathogenic microbes. Beyond host immunity, an important factor determining the ability of pathogens to invade and proliferate in a host is the resident microbiota, but we are only beginning to glimpse its multifarious impacts. We know even less about interactions among pathogenic microbes themselves. Any effort to explain how pathogen communities, or pathobiota, develop within a host requires knowledge about the extent to which pathogens engage in competition, commensalism and cooperation, both with other pathogens and the rest of the microbiota. In the PATHOCOM project (https://figshare.com/articles/preprint/PATHOCOM_proposal/13174337), we aim at setting up a program that integrates large-scale field observations of microbiota/pathobiota in the plant Arabidopsis thaliana with ultra-high-throughput experimental tests of host-dependent interactions among microbes, allowing predicting stable pathogen-pathogen-microbiota interactions by modelling. In this context, the postdoctoral project is part of the first stages of the PATHOCOM project and aims to characterize the intra- and interspecific diversity as well as abundance of pathobiota and commensal microbiota across multiple populations of A. thaliana in south-west of France, together with information on environmental variables and host genotypes. This 36-month postdoctoral project is funded by the ERC (European Research Council) and will be carried out as part of an interdisciplinary and collaborative project with the research groups of Detlef Weigel (Max Planck Institute, Tubingen, Germany) and Joy Bergelson (New-York University, USA).
The post-doc will be in charge of characterizing the microbiota/pathobiota and the abiotic (climate, soil agronomic properties...) and biotic (plant communities ...) environment of more than 20 natural populations of A. thaliana located southwest of France both in autumn and spring, over 3 years. The post-doc will interact with two other post-docs located in Tubingen and New-York, who will perform a similar characterization of more than twenty natural populations of A. thaliana in Germany and USA. In addition, the post-doc will be assisted in his / her activities by an engineer assistant.
Applicants should have strong skills in ecological genomics, involving experiences in field work and lab work (mainly microbiology), as well as skills in handling large datasets and statistical analysis. We expect applicants to have obtained a PhD related to ecological genomics. Fluent English is required.
The LIPM offers an excellent scientific environment of teams working on plant-microbe or plant-plant interactions (https://en.lipme.fr/). As a member of the LabEx (Laboratory of Excellence) TULIP (https://www.labex-tulip.fr/labex-tulip_eng/) and of the FR AIB Research Federation (http://www.fraib.fr/), the LIPME also benefits from key interactions with other relevant plant and ecology labs, local facilities and platforms (including in imagery and high-throughput phenotyping).
For more information about the ECOGEN team: https://en.lipme.fr/ecogen-1
Constraints and risks
The postdoctoral fellow will be located at the LIPME, but will have to spend every year short stays (2-3 weeks) in the research groups of Detlef Weigel and Joy Bergelson. The laboratory is governed by internal regulations.
Please submit your CV, cover letter and 2 letters of recommendation directly to this website. Any document sent directly to the address firstname.lastname@example.org will not be considered.
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