PhD Position (M/F) – Functional Retinal Imaging using Full-Field OCT

New

Institut Langevin

PARIS 05 • Paris

  • FTC PhD student / Offer for thesis
  • 36 mounth
  • Doctorate

This offer is available in English version

This offer is open to people with a document recognizing their status as a disabled worker.

Offer at a glance

The Unit

Institut Langevin

Contract Type

FTC PhD student / Offer for thesis

Working hHours

Full Time

Workplace

75238 PARIS 05

Contract Duration

36 mounth

Date of Hire

01/10/2026

Remuneration

2300 € gross monthly

Apply Application Deadline : 13 May 2026 23:59

Job Description

Thesis Subject

Development of Experimental and Computational Methods for Functional Imaging of Retinal Neurons using Full-Field OCT

Your Work Environment

Scientific Context

The retina is the only part of the central nervous system that can be directly observed in vivo in humans. It therefore provides a unique model for studying neurovascular coupling and its early alterations in neurodegenerative diseases such as Alzheimer's disease.

In this context, the team at Institut Langevin develops advanced optical imaging techniques that enable the observation of nanometric structural changes associated with retinal neuron activity following light stimulation. These approaches open new perspectives for studying neuronal function and neurovascular interactions at the cellular scale.

This PhD project is part of the European ERC MIRACLE-AD program, which aims to develop novel optical biomarkers of retinal neuronal function.

Objectives of the PhD

The project relies on a Full-Field Optical Coherence Tomography (FF-OCT) retinal imaging system capable of acquiring high-speed 3D volumes.

The objective of the PhD is to develop methods to extract functional neuronal signals from these complex volumetric datasets.

More specifically, the project will involve:

operation and optimization of the FF-OCT imaging system;
development of algorithms for volumetric image stabilization;
extraction of functional signals associated with retinal neuronal activity;
quantitative analysis of neuronal dynamics.
Research Environment

The PhD will be carried out at the Institut Langevin (CNRS – ESPCI Paris – PSL University), a leading international research laboratory in optics and imaging.

The PhD student will join the CLARITY research group, which specializes in the development of advanced optical imaging systems for cellular-resolution imaging of the human retina.

The project will take place in a strong interdisciplinary environment, with close collaborations with clinicians and researchers from the Quinze-Vingts National Ophthalmology Hospital.

Compensation and benefits

Compensation

2300 € gross monthly

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

Offer reference UMR7587-PEDBAR-011
CN Section(s) / Research Area Micro and nanotechnologies, micro and nanosystems, photonics, electronics, electromagnetism, electrical energy

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions

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PhD Position (M/F) – Functional Retinal Imaging using Full-Field OCT

FTC PhD student / Offer for thesis • 36 mounth • Doctorate • PARIS 05

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