PhD (M/F) in development of machine learning methods for single-cell omics data integration

Biologie du Développement et Cellules Souches

PARIS 15 • Paris

  • FTC PhD student / Offer for thesis
  • 36 mounth
  • BAC+5

This offer is available in English version

This offer is open to people with a document recognizing their status as a disabled worker.

Offer at a glance

The Unit

Biologie du Développement et Cellules Souches

Contract Type

FTC PhD student / Offer for thesis

Working hHours

Full Time

Workplace

PARIS 15 ()

Contract Duration

36 mounth

Date of Hire

01/05/2026

Remuneration

2300 € gross monthly

Apply Application Deadline : 01 May 2026 00:00

Job Description

Thesis Subject

Single-cell high-throughput sequencing, extracting huge amounts molecular data from a cell, is creating exciting opportunities for machine learning to address outstanding biological questions. The PhD (M/F), to be recruited in the context of the ERC StG MULTI-viewCELL, will be working on the development of a new method combining machine learning and biophysical modelling to model embryo development from spatial transcriptomics data.

Activities :
- design of a new mathematical method
- monitoring and study of publications relevant to the field
- programming/coding in Python (Pytorch)
- presentation of results at conferences
- interaction with team members and international collaborators

Degree : Master of Physics, data science, computer science, applied mathematics

We expect a candidate with a strong background in physics and/or machine learning. The candidate must also be proficient in high-level languages like Python. Familiarity with single-cell data and experience with existing single-cell methods and software would represent a strong advantage. Excellent communication skills and team spirit, and an ability to work in autonomy are essential. Fluent English both spoken and written is required.

Your Work Environment

The Machine Learning for Integrative Genomics team (https://research.pasteur.fr/en/team/machine-learning-for-integrative- genomics/) at Institut Pasteur, led by Laura Cantini, works at the interface of machine learning and biology (tools developed by the team: https://github.com/cantinilab). The team is composed of 9 people : 4PhD students, 3 post doc, 1 research engineer and 1 assistant. The team is associated with the Institut Pasteur's Computational Biology Department, UMR3738 and the PRAIRIE Artificial Intelligence Institute. The team recently won ERC StG funding, which is the subject of this recruitment.

MULTIview-CELL ERC StG :
https://www.ins2i.cnrs.fr/fr/cnrsinfo/laura-cantini-un-projet-erc-starting-grant-linterface-entre-apprentissage-automatique-et
https://research.pasteur.fr/en/project/multi-viewcell/

Compensation and benefits

Compensation

2300 € gross monthly

Annual leave and RTT

44 jours

Remote Working practice and compensation

Pratique et indemnisation du TT

Transport

Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€

About the offer

Offer reference UMR3738-DEBPHI-006
CN Section(s) / Research Area Mathematics and mathematical interactions

About the CNRS

The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.

CNRS

The research professions

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PhD (M/F) in development of machine learning methods for single-cell omics data integration

FTC PhD student / Offer for thesis • 36 mounth • BAC+5 • PARIS 15

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