Postdoctoral position on the role of CLDN1 (M/F)
New
- Researcher in FTC
- 6 mounth
- Doctorate
This offer is available in English version
This offer is open to people with a document recognizing their status as a disabled worker.
Offer at a glance
The Unit
Institut de génétique et de biologie moléculaire et cellulaire
Contract Type
Researcher in FTC
Working hHours
Full Time
Workplace
67404 ILLKIRCH GRAFFENSTADEN
Contract Duration
6 mounth
Date of Hire
01/05/2026
Remuneration
Starting at 3,071.50 to 3,501.51, depending on experience
Apply Application Deadline : 14 April 2026 23:59
Job Description
Missions
The postdoctoral fellow's work involves evaluating the role of CLDN1 in the growth of xenograft tumors and determining how CLDN1 modulates the tumor microenvironment. The transmembrane protein CLDN1 plays an important role in cancer cell signaling. The host team has demonstrated its immunomodulatory role in cutaneous melanoma, and this project aims to evaluate its potential as a therapeutic target.
Activity
o Perform xenografts of murine melanoma cells in isogenic immunocompetent mice. o Assess tumor growth and collect tumor samples for histological and molecular analysis. o Analyze high-throughput transcriptomic and genomic data. o Perform immunostains on tumor sections.
Your Profil
Skills
Knowledge: - The candidate must have recently completed a Ph.D. in molecular and cellular biology of melanoma, with a strong understanding of immuno-oncology and the functioning of the immune system, and publications in at least one of these fields. Skills: - The candidate must have solid experience in cell biology, the culture and analysis of melanoma cell lines, and the generation, management, and analysis of xenograft tumors; generation and analysis of high-throughput genomic data, transcriptomics, and scRNA-seq Interpersonal Skills: - The candidate must be able to integrate into a multidisciplinary team, interact and communicate with people from different fields; fluency in English (C1 level of the Common European Framework) is essential. Candidates must hold animal experimentation authorization at the designer and experimenter levels.
Your Work Environment
The CNRS (National Center for Scientific Research), which holds the HR Excellence in Research designation, is one of the world's leading public multidisciplinary research organizations. The IGBMC (Institute of Genetics and Molecular and Cellular Biology), one of Europe's leading biomedical research centers, is a Joint Research Unit affiliated with the CNRS, INSERM, and the University of Strasbourg. The successful candidate will work at the IGBMC and benefit from an exceptional international scientific environment. The IGBMC comprises some forty research teams divided into four scientific departments and state-of-the-art technological platforms located on site. The successful candidate will have access to the CROUS cafeteria. The site is accessible by tram (Line A, Campus Illkirch station) from Strasbourg train station or by car (parking available). Public transportation costs are partially covered.
Compensation and benefits
Compensation
Starting at 3,071.50 to 3,501.51, depending on experience
Annual leave and RTT
44 jours
Remote Working practice and compensation
Pratique et indemnisation du TT
Transport
Prise en charge à 75% du coût et forfait mobilité durable jusqu’à 300€
About the offer
| Offer reference | UMR7104-MARMEN-002 |
|---|---|
| CN Section(s) / Research Area | Cellular biology, development, evolution-development, reproduction |
About the CNRS
The CNRS is a major player in fundamental research on a global scale. The CNRS is the only French organization active in all scientific fields. Its unique position as a multi-specialist allows it to bring together different disciplines to address the most important challenges of the contemporary world, in connection with the actors of change.
Create your alert
Don't miss any opportunity to find the job that's right for you. Register for free and receive new vacancies directly in your mailbox.