General information
Offer title : POST-DOC in SUPRAMOLECULAR CHEMICAL BIOLOGY M/F (H/F)
Reference : UMR5247-SEBULR-006
Number of position : 1
Workplace : MONTPELLIER
Date of publication : 04 September 2025
Type of Contract : Researcher in FTC
Contract Period : 24 months
Expected date of employment : 5 January 2026
Proportion of work : Full Time
Remuneration : from 3021.50€ gross/month, adapted according to experience
Desired level of education : Doctorate
Experience required : Indifferent
Section(s) CN : 16 - Chemistry of and for life: design and properties of molecules of biological interest
Missions
Our team is interested in the self-assembly of bioactive entities for the recognition and delivery of drugs (e.g. photosensitizers, nucleic acids) and application in photodynamic therapy (PDT) and RNA-based therapies (Chem. Comm., 2025, 61, 4050-4053; Chem. Sci., 2025, 16, 2413-2419; Org. Biomol. Chem., 2024, 22, 1484-1494; Chem. Eur. J., 2023, 29, 7, e202202921; Chem. Sci., 2022, 13, 909-933; Biomacromolecules, 2022, 23, 1, 431-442; Angew. Chem. Int. Ed., 2021, 60, 11, 5783-5787; Acc. Chem. Res., 2019, 52, 2, 510-519). In the context of a new ANR-funded project (HiOF, 2026-2030), we will investigate the self-assembly of peptide-aromatic conjugates into fluorescent nanostructures, which growth results from a combination of dynamic covalent and supramolecular processes, moving from solution studies to model lipid membranes, then live cells.
Activities
Motivated and enthusiastic PhD chemist with 0-2 years post-PhD experience, a main background in supramolecular chemistry and a keen interest in chemical biology. You will be involved in the synthesis of aromatic and peptide building blocks and their hierarchical self-assembly into supramolecular polymers, first in solution then in more complex biological environments.
Skills
Organic synthesis, peptide synthesis, caracterisation of supramolecular assemblies
Work Context
The Institut des Biomolécules Max Mousseron (IBMM, ca. 320 employees, 16 teams) focuses on the chemical synthesis, molecular and supramolecular engineering, and the pharmacological study of biomolecules (e.g. nucleosides/nucleotides/nucleic acids, peptides/proteins, glycosides, lipids), as well as their analogues, derivatives and conjugation products, for health applications. The project will be carried out at the Glycochemistry & Molecular Recognition team (Sébastien ULRICH) in the new Balard building which is equipped with state-of-the-art characterization techniques at UAR PAC Chimie Balard.
The position is located in a sector under the protection of scientific and technical potential (PPST), and therefore requires, in accordance with the regulations, that your arrival is authorized by the competent authority of the MESR.
Constraints and risks
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