General information
Offer title : Postdoc in regenerative biology: tracking the cellular origins regeneration (M/F) (H/F)
Reference : UMR5242-MICAVE-017
Number of position : 1
Workplace : LYON 07
Date of publication : 14 October 2025
Type of Contract : Researcher in FTC
Contract Period : 12 months
Expected date of employment : 1 January 2026
Proportion of work : Full Time
Remuneration : 3020 to 4200 € gross salary per month, depending on research experience
Desired level of education : Doctorate
Experience required : Indifferent
Section(s) CN : 22 - Cellular biology, development, evolution-development, reproduction
Missions
We are seeking a highly-motivated postdoctoral researcher to investigate the cellular basis of regeneration in the crustacean Parhyale hawaiensis. The project will focus on identifying progenitor cells that underpin leg regeneration, focusing on the sensory organ lineages of the leg.
Activities
The selected researcher will:
• Be trained in the live imaging and transgenic approaches available in Parhyale (https://elifesciences.org/articles/107534, www.tinyurl.com/parhyale1).
• Generate fluorescent markers for the various cell types that constitute the leg's sensory organs, including neurons, setae, support cells and glia.
• Use long-term live imaging and cell tracking to identify the progenitors of these cells during regeneration.
• Develop and apply a recombinase-based cell barcoding strategy to trace cell lineages during leg growth and regeneration.
The researcher will work in close collaboration with our international partners Jan Huisken and Mette Handberg-Thorsager (light-sheet microscopy), Marco Grillo (barcode-based cell tracking), Jean-Yves Tinevez and Ko Sugawara (AI-based cell tracking) and Théo Vart (video-game-based tracking and outreach).
Skills
• PhD in developmental biology, or related fields such as regenerative biology, cell biology, molecular genetics
• Experience in microscopy (preferably live imaging), lineage tracing, and/or the development and use of transgenic tools
• Collaborative spirit and ability to communicate fluently in English
Candidates should submit a CV, a cover letter outlining their motivation for applying to this project, relevant research experience and interests, and contact information for three referees.
Work Context
The Institut de Génomique Fonctionnelle de Lyon (IGFL) is an internationally renowned research centre. Scientific innovation and interdisciplinary collaborations are at the heart of our activities. The recruited postdoc will join the Development, Regeneration and Evolution team (www.averof-lab.org) and will participate in the team's weekly meetings, seminars, retreats and outreach activities. The team is international and our working language is English.
The project is funded for 3+ years by a grant from the Agence Nationale de la Recherche. The project will be supervised by Michalis Averof. The initial contract will be for 1 year, renewable up to 3+ years. The envisaged starting date is in early 2026.
Constraints and risks
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