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Reference : UMR7592-BENLAD-004
Workplace : PARIS 13
Date of publication : Monday, May 03, 2021
Scientific Responsible name : Benoit Ladoux
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 October 2021
Proportion of work : Full time
Remuneration : 2 135,00 € gross monthly
Description of the thesis topic
Collective cell movements give rise to complex changes in multicellular tissue structures, including epithelial regeneration, morphogenesis, and invasion of cell masses during cancer progression, and thus integrate both adhesion to the ECM and to neighboring cells. Mechanical external constraints have been shown to influence both in vivo and in vitro collective migration behaviours. We will study cell migration and tissue homestasis. We will use microfabrication, microscopy , cell mechanical tools and cell biology methods.
Our group is part of the Institut Jacques Monod (https://www.ijm.fr), which is housed in a brand new building on the new Paris campus. The Institut Jacques Monod is one of the leading public centers for basic research in biology in Paris and offers a state-of-the-art research environment. It offers a rich, multidisciplinary environment, as well as access to different experimental approaches within our laboratory and technological platforms to ensure proper research development. The Thesis will be supervised by B. Ladoux.
Constraints and risks
Nothing to declare
Looking for motivated candidates to work at the interface between Physics and Biology.
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