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Reference : UMR7272-CORMEI-002
Workplace : NICE
Date of publication : Wednesday, January 09, 2019
Scientific Responsible name : Cornelia Meinert
Type of Contract : PhD Student contract / Thesis offer
Contract Period : 36 months
Start date of the thesis : 1 April 2019
Proportion of work : Full time
Remuneration : 1 768,55 € gross monthly
Description of the thesis topic
What is responsible for the emergence of homochirality, the almost exclusive use of one enantiomer over its mirror image? And what led to the evolution of life's homochiral biopolymers, DNA/RNA, proteins and lipids, where all the constituent monomers exhibit the same handedness?
A synergistic methodology will be developed in A-LIFE to build a unified theory for the origin of all chiral biological building blocks and their assembly into homochiral supramolecular entities. Multidimensional gas chromatographic analyses of astrophysical-relevant samples (e.g. ice analogues & meteorites) will be combined with asymmetric photochemistry triggered by circularly polarized synchrotron and laser sources. Intermediates and autocatalytic reaction kinetics will be monitored to understand the underlying processes. A unified theory on the asymmetric formation and self-assembly of life's biopolymers will impact the conceptual foundation of the origin of life.
- M.Sc. (or equivalent) in chemistry, preferably specialized in analytical chemistry
• The possibility to be involved in a timely research project in an emerging field, using state-of-the art equipment
• A stimulating, diverse and international research team & advanced training opportunities, embedded in a networked research environment
Constraints and risks
no particular risks
Starting date: 1st April, 2019; possibility to postpone the starting date
Applications written in English, German or French should be sent to Dr. Meinert (firstname.lastname@example.org) and should include(combined as one pdf file):
(1) cover letter
(2) CV including your scientific skills, your research experience and a complete list of publications
(3) a 2-page summary of your Master thesis
(4) a transcript of results from the university-level courses taken
(5) contact information for at least 2 referees (recommendation letters should be sent directly to Dr. Meinert)
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